<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27735

Description Mediator of RNA polymerase II transcription subunit 17
SequenceMSGVRAVRISIESACEKQVQEVGLDGTETYLQPLSMSQNLARLAQRIDFSQGSGSEEEEAAGAEGDAQDWAGSGSSADQDDEEGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPFPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPKIGLQLLISLCHSSNDKKSQKSATEKQSPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRRTAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDSKWNHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCL
Length653
PositionHead
OrganismAiluropoda melanoleuca (Giant panda)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.433
Instability index56.74
Isoelectric point7.66
Molecular weight73127.52
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27735
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     816.67|     273|     343|      10|     312|       1
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   10-  312 (400.22/384.37)	SIESACEKQVQEVGLDGTETYLQPL...SMSQNLARLAQRIDFSQGSGSEEEEAAGAEGDAQDWAGSGSSADQDDEEgLVKFQPSLWpwdsvrnnLRSALTEMCVlyDVL.SIVRDKKFM....TLDPVSQDALPPKQNPQTLQLISKKKSL...AGAAQIllKGAERLTKSVT.ENQENKLQrDFnsELLRLRQHwKLRKVGD..KILG..DLSYRSAGSLfphhGTFEVIKNTDIDLDKKIPEDYCpldVQIPSDLEGSAYIKVSIQK.QAPDI..GDL...GTVNLFKRPFPKSKpgsphWqTKLEAAQNVLLCKEIFAQLS
  356-  650 (416.45/304.96)	SQKSATEKQSPEDHLYVLEHNLHLLireFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQSSEGLLEK.IIKQAKHIF........LRSRRTAATI..DSLaSRIEDPQIQahwsNINDVYESSVKVLITSQGYEQICKSIQLqlnIGVEQI..RVVHRDGRVITlSHQEQELQ.DF..LLSQMSQH.QVHAVQQlaKVMGwqVLSFSNHVGL....GPIESIGNASAITVASPSGDYA...ISVRNGPESGSKIMVQFPRnQCKDLpkSDVlqdSKWNHLRGPFKEVQ.....W.NKMEGRNFVYKMELLMSALS
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27735 with Med17 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) QGSGSEEEEAAGAEGDAQDWAGSGSSADQDDEE
51
83

Molecular Recognition Features

MoRF SequenceStartStop
1) LARLAQRIDF
40
49