<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27695

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSNLSQESHEQCIQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLLNSDNLEWERTQLWSLTFKLVQKIIGGVDYKGVRDLLKGILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRTPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSNLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNEPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTIENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHIRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQTQSQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEGHLRERPSLKRKLVHSIIGSLKDNRPQGWCLSETYLKCAMNAREDNPWIPDDIYYCKLIARLVDTMAGKSPSPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKEVGNALLNVVLKSQPLVPRDNITAWMNAIGLIITALPEPYWIVLHERIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMCCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLLEVDQCNTHLNYMDPICDFLYHVKYMFTGDSVKDQVEKIICNLRPALKLRLRFIHISKMDSASVPQQSISTVSPASQPPQVPVNIALPVSQ
Length1369
PositionTail
OrganismAnolis carolinensis (Green anole) (American chameleon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Lepidosauria> Squamata> Bifurcata> Unidentata> Episquamata> Toxicofera> Iguania> Dactyloidae> Anolis.
Aromaticity0.10
Grand average of hydropathy-0.024
Instability index46.93
Isoelectric point6.92
Molecular weight156794.40
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27695
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.44|      18|      19|    1005|    1022|       1
---------------------------------------------------------------------------
 1003- 1020 (34.53/22.77)	TYLYNTLHYYEGHLRE.RP
 1021- 1039 (24.92/14.27)	SLKRKLVHSIIGSLKDnRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.39|      17|      19|     244|     262|       2
---------------------------------------------------------------------------
  244-  262 (28.00/19.98)	DPTT..LRFPLKglLPYDKDL
  264-  282 (28.39/13.97)	EPQTalLRYVLE..QPYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.61|      24|      89|    1067|    1092|       3
---------------------------------------------------------------------------
 1067- 1092 (43.58/35.78)	YYCKLIARLVDTMagKSPSPFPNCDW
 1160- 1183 (44.03/28.99)	YWIVLHERIVSVI..NSPSLTSETEW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.61|      17|      19|     894|     911|       4
---------------------------------------------------------------------------
  894-  911 (26.11/17.66)	NDFRNRVSDFVKEnSPEH
  915-  931 (34.51/19.20)	NDWHTKHMSYHKK.YPEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.17|      27|      89|    1184|    1213|       5
---------------------------------------------------------------------------
 1184- 1213 (49.67/36.35)	VGYPF..QLFDFTAC..HQSYSEMCCSYtlaLAH
 1270- 1300 (43.50/24.62)	IGVAFyeMLLEVDQCntHLNYMDPICDF...LYH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      19|     351|     362|       6
---------------------------------------------------------------------------
  351-  362 (21.06/13.04)	HMVLSLHQKLAG
  371-  382 (22.76/14.74)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.83|      19|      21|     815|     834|       7
---------------------------------------------------------------------------
  815-  834 (27.25/26.25)	GARALVAHIRTFADfLVYEF
  839-  857 (35.58/27.84)	GGQQLNKCIEILND.MVWKY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.10|      62|      79|     450|     525|      12
---------------------------------------------------------------------------
  450-  525 (103.21/87.42)	SLKLHHEF.LQQSLRNKSLQMNDYKIAL.LCNAystnsecftlpmgvLVET.....IYGN.......GNMRTPLPGT.NCMASGSI.TPLPM
  530-  607 (74.89/42.87)	SLTVHAKMsLIHSIATRVIKLAHAKSSLaLAPA..............LVETysrllVYMEieslgikGFISQLLPTVfKSHAWGILhTLLEM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.88|      27|     293|     937|     963|      13
---------------------------------------------------------------------------
  937-  963 (51.39/37.68)	LAEQVNPPVQTQSQYLPIY..FGNVCLRF
 1231- 1259 (43.50/30.58)	LTEVLIPIVKTEFQLLYVYhlVGPFLQRF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.45|      17|      80|    1041|    1061|      16
---------------------------------------------------------------------------
  711-  727 (37.05/17.27)	WC..KDILQTIMNFTPHN.W
 1042- 1061 (27.40/21.21)	WClsETYLKCAMNAREDNpW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.59|      17|     462|     634|     650|      17
---------------------------------------------------------------------------
  634-  650 (30.63/18.25)	PQ....TNQNQLHLCVESTAL
  663-  683 (20.96/10.20)	PQftrfLNEPKTVLSAESEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.03|      36|     680|      38|      73|      19
---------------------------------------------------------------------------
   38-   73 (71.60/56.38)	ISCLGA.FRQFW..SNLSQESH........EQCIQW........IVRFIHSQHSP
  732-  786 (46.43/33.29)	LSCFPApLQAFFkqNNVPQESRfnlkknveEEYRKWksmtiendIITHFSMQGSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27695 with Med23 domain of Kingdom Metazoa
Unable to open file!