<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27686

Description Uncharacterized protein
SequenceMTPNKYILTPPEELYPYTGRTEKERNDDKSCIYPDFEAWSHTLEDDQILNKFVAKGYYTTSKVNFESISARSTLNKPLNTVSIQLANQFTKILQVREQEINRIPSKDKNSPNATTFFPLSGPYFSLPNRVTLTDHRKELWLQELSNPYVSLSKISKFIPHGLKRRQVLEQCYTKQIPLKRAIWLIKCCFSIEWKSLMTKASQTQADTNKQLLKEWTDNFIYILEKLIFEISQHYNDPNQMKNWKLQISYFLKLLGNSYTLQLLEKETFHHWLVEFVTKVENLKFLPLSLHILTTFWDGICQPIESADENGTATLTQPLFLVSKITDMLLQKYASISQSKSMINDERYIINDLKKNNKIKDSLLSTLKLLICKLFQEQSLEVFLFSAANWEIYKPYLYEATSLLNKTVEATTEVRKKLELISYSNEALKNGPSLVRVDDSENDVKLIMSPTTTGNNIHFDAIHLKYVDTKLTKKLDDNPTSFDWSSYIDQNDFQCSKVVQLILWSICPSRQMHYEAHQLVAKLLLLKINSVDGFPDFQIEDTIWTLVFQIAKLSERNKALRASLPSLSKLLNILITYGIIKVPTYIRKLISSGVLYLPNSNGKFVHCKILINLKISPLMKSQYNMVLRNVMEYDPTFFEKYNFDQLQRDAEDIRNNIANIDDLELDQCPLSVKTIIAEWYLSNLCSDTQSMVDKVRLLKNFKLFCIDLELSHHYYKWIEFIVYHQLLIDIEALETLMDILLCYEKVFSQFINDHILFTKTFIFIYRKVLRDKDNDTYMVTSFMPFWKFFKKNFMLALNIDNDLNIELTNVYEEEKQKQELLEKDQMEVQRIYNCINSNTSRKVWKFTEVFEGNVKLMITKQTSTEKRRLARRNLHLLMIANLRDYNKRMSVFLKRKYFQKEDLIRLVSNKLLTLGQIQSILGIEFIIPFLSLKTMDDGQYFEYHKEKYIESNFAVILTACENNFSQFYQLFLSLFVKYGMMTKLFSTAAKSLISLLKRNSSTSNVIMEDLLKYQIKEFTLQSDLKDEQNITSEGEDDDDHTIEEPKASDLYTNLDFSNLWIFQIFTCYQLNEMLELNNLDSNVNMFISEVVEITQYDNLCTRIFDQLKNTKIITTVIVVVERVFLERCLSQLVISNESLIFIIEVIETLSKKINKDSSGNIPMADDCYSLFQQTMSYFANLDINKLTDLESILDVFFKIFSIHQNPIFRLILNSLGGRISDRQEEEKFIDNMFTVFGKLTFNLRLKLMLYEILSGFKSYSIYVSTRSNEENNGEQTLVILDQDLITRKMSKLPPFQVSSFTKEPSDEDDDSKLTLGTQFIDINPTDNGNRANISQDGKSSKWFIYNKEEKTYVSVFKDEPYHNINNYQPDTNNSSNNSCLNLSLFEASFERKNPR
Length1394
PositionKinase
OrganismNaumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Naumovozyma.
Aromaticity0.11
Grand average of hydropathy-0.292
Instability index40.44
Isoelectric point6.08
Molecular weight163258.75
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27686
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.63|      32|     327|     549|     580|       1
---------------------------------------------------------------------------
  549-  580 (51.82/32.28)	IAKLSERNKALRASL.......PSLSKLL.NILITYGIIK
  878-  917 (42.81/25.38)	IANLRDYNKRMSVFLkrkyfqkEDLIRLVsNKLLTLGQIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.35|      21|      25|    1052|    1072|       4
---------------------------------------------------------------------------
 1052- 1072 (39.96/27.84)	NLDFS.NLWIFQIFTCYQLNEM
 1077- 1098 (31.38/20.05)	NLDSNvNMFISEVVEITQYDNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.25|      15|      25|     212|     226|       5
---------------------------------------------------------------------------
  212-  226 (25.32/15.29)	LKEWTDNFIYILEKL
  240-  254 (24.33/14.37)	MKNWKLQISYFLKLL
  268-  282 (24.59/14.61)	FHHWLVEFVTKVENL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.27|      38|     331|     321|     371|       6
---------------------------------------------------------------------------
  328-  367 (54.34/55.53)	LLQKYASiSQSKSMI.......NDERYIINDLKKnNKIKD.SLLSTLK
  979- 1024 (51.93/21.16)	MMTKLFS.TAAKSLIsllkrnsSTSNVIMEDLLK.YQIKEfTLQSDLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.20|      17|     409|     784|     814|       7
---------------------------------------------------------------------------
  798-  814 (28.68/ 8.19)	IDNDLNIELTNVYEEEK
 1210- 1226 (28.53/15.88)	ILNSLGGRISDRQEEEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.41|      27|     458|     642|     670|       8
---------------------------------------------------------------------------
  642-  670 (38.22/38.46)	FDQLqRDAEDIRNNIANIDDLELDQCpLS
 1103- 1129 (45.19/32.76)	FDQL.KNTKIITTVIVVVERVFLERC.LS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.57|      17|      20|     604|     623|      10
---------------------------------------------------------------------------
  604-  623 (24.98/22.99)	VHCKIlinLKISPLMKSQYN
  625-  641 (30.59/18.89)	VLRNV...MEYDPTFFEKYN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.12|      32|     410|     402|     451|      12
---------------------------------------------------------------------------
  414-  450 (48.20/55.17)	RKKLELISYSNEALKNGPSlvrvdDSENDVKLIM.......SPT
 1286- 1324 (49.92/19.91)	RKMSKLPPFQVSSFTKEPS.....DEDDDSKLTLgtqfidiNPT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27686 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) YILTPPEELY
6
15