<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27686

Description Uncharacterized protein
SequenceMTPNKYILTPPEELYPYTGRTEKERNDDKSCIYPDFEAWSHTLEDDQILNKFVAKGYYTTSKVNFESISARSTLNKPLNTVSIQLANQFTKILQVREQEINRIPSKDKNSPNATTFFPLSGPYFSLPNRVTLTDHRKELWLQELSNPYVSLSKISKFIPHGLKRRQVLEQCYTKQIPLKRAIWLIKCCFSIEWKSLMTKASQTQADTNKQLLKEWTDNFIYILEKLIFEISQHYNDPNQMKNWKLQISYFLKLLGNSYTLQLLEKETFHHWLVEFVTKVENLKFLPLSLHILTTFWDGICQPIESADENGTATLTQPLFLVSKITDMLLQKYASISQSKSMINDERYIINDLKKNNKIKDSLLSTLKLLICKLFQEQSLEVFLFSAANWEIYKPYLYEATSLLNKTVEATTEVRKKLELISYSNEALKNGPSLVRVDDSENDVKLIMSPTTTGNNIHFDAIHLKYVDTKLTKKLDDNPTSFDWSSYIDQNDFQCSKVVQLILWSICPSRQMHYEAHQLVAKLLLLKINSVDGFPDFQIEDTIWTLVFQIAKLSERNKALRASLPSLSKLLNILITYGIIKVPTYIRKLISSGVLYLPNSNGKFVHCKILINLKISPLMKSQYNMVLRNVMEYDPTFFEKYNFDQLQRDAEDIRNNIANIDDLELDQCPLSVKTIIAEWYLSNLCSDTQSMVDKVRLLKNFKLFCIDLELSHHYYKWIEFIVYHQLLIDIEALETLMDILLCYEKVFSQFINDHILFTKTFIFIYRKVLRDKDNDTYMVTSFMPFWKFFKKNFMLALNIDNDLNIELTNVYEEEKQKQELLEKDQMEVQRIYNCINSNTSRKVWKFTEVFEGNVKLMITKQTSTEKRRLARRNLHLLMIANLRDYNKRMSVFLKRKYFQKEDLIRLVSNKLLTLGQIQSILGIEFIIPFLSLKTMDDGQYFEYHKEKYIESNFAVILTACENNFSQFYQLFLSLFVKYGMMTKLFSTAAKSLISLLKRNSSTSNVIMEDLLKYQIKEFTLQSDLKDEQNITSEGEDDDDHTIEEPKASDLYTNLDFSNLWIFQIFTCYQLNEMLELNNLDSNVNMFISEVVEITQYDNLCTRIFDQLKNTKIITTVIVVVERVFLERCLSQLVISNESLIFIIEVIETLSKKINKDSSGNIPMADDCYSLFQQTMSYFANLDINKLTDLESILDVFFKIFSIHQNPIFRLILNSLGGRISDRQEEEKFIDNMFTVFGKLTFNLRLKLMLYEILSGFKSYSIYVSTRSNEENNGEQTLVILDQDLITRKMSKLPPFQVSSFTKEPSDEDDDSKLTLGTQFIDINPTDNGNRANISQDGKSSKWFIYNKEEKTYVSVFKDEPYHNINNYQPDTNNSSNNSCLNLSLFEASFERKNPR
Length1394
PositionKinase
OrganismNaumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Naumovozyma.
Aromaticity0.11
Grand average of hydropathy-0.292
Instability index40.44
Isoelectric point6.08
Molecular weight163258.75
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27686
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.63|      32|     327|     549|     580|       1
---------------------------------------------------------------------------
  549-  580 (51.82/32.28)	IAKLSERNKALRASL.......PSLSKLL.NILITYGIIK
  878-  917 (42.81/25.38)	IANLRDYNKRMSVFLkrkyfqkEDLIRLVsNKLLTLGQIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.35|      21|      25|    1052|    1072|       4
---------------------------------------------------------------------------
 1052- 1072 (39.96/27.84)	NLDFS.NLWIFQIFTCYQLNEM
 1077- 1098 (31.38/20.05)	NLDSNvNMFISEVVEITQYDNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.25|      15|      25|     212|     226|       5
---------------------------------------------------------------------------
  212-  226 (25.32/15.29)	LKEWTDNFIYILEKL
  240-  254 (24.33/14.37)	MKNWKLQISYFLKLL
  268-  282 (24.59/14.61)	FHHWLVEFVTKVENL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.27|      38|     331|     321|     371|       6
---------------------------------------------------------------------------
  328-  367 (54.34/55.53)	LLQKYASiSQSKSMI.......NDERYIINDLKKnNKIKD.SLLSTLK
  979- 1024 (51.93/21.16)	MMTKLFS.TAAKSLIsllkrnsSTSNVIMEDLLK.YQIKEfTLQSDLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.20|      17|     409|     784|     814|       7
---------------------------------------------------------------------------
  798-  814 (28.68/ 8.19)	IDNDLNIELTNVYEEEK
 1210- 1226 (28.53/15.88)	ILNSLGGRISDRQEEEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.41|      27|     458|     642|     670|       8
---------------------------------------------------------------------------
  642-  670 (38.22/38.46)	FDQLqRDAEDIRNNIANIDDLELDQCpLS
 1103- 1129 (45.19/32.76)	FDQL.KNTKIITTVIVVVERVFLERC.LS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.57|      17|      20|     604|     623|      10
---------------------------------------------------------------------------
  604-  623 (24.98/22.99)	VHCKIlinLKISPLMKSQYN
  625-  641 (30.59/18.89)	VLRNV...MEYDPTFFEKYN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.12|      32|     410|     402|     451|      12
---------------------------------------------------------------------------
  414-  450 (48.20/55.17)	RKKLELISYSNEALKNGPSlvrvdDSENDVKLIM.......SPT
 1286- 1324 (49.92/19.91)	RKMSKLPPFQVSSFTKEPS.....DEDDDSKLTLgtqfidiNPT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27686 with Med12 domain of Kingdom Fungi
Unable to open file!