<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27684

Description Uncharacterized protein
SequenceMSSIGKDTLTAAERSSNVSELLQVLMDINEINGGNSETASKMKVHAKNFENALYAKSSSRKEYLDSMREKVNAMRETRDSRKKAINSRSNDQNINYIPNPNISNTNTNANTNNNNNINMDPQAFLNQQAQARQQAAMQLKNRQQQQQQQQQQQQPQQRLTPQQQQLINQMKVATIPRELLQKIPNVPAGVTTWQQITELAQQKILSQDDMTVAKEMYKLHQQLLFKSKLQQQQQQQQLSQQQQQRQGQQGQGQVLPPQQQQLQQQQQQLQQQQQQPRGTSVSTNQNPNQQRARGQQPQQQQQQQREIPNVLGQINEIFTTEEQRALLQEAMEACKNYQKNQFGNMTTVPEQARQLFIRKYINQKVLKKIQSVRLAQAAAMAATNNNKPMPQQQQQHQQQQQQQQQQTRVQATQNQGPMQQAQIQLQPQQRSGIPNATPSSAGYKSSQVPTPQGNNIGGVNNNSTNNNNNNNNNNMSTSRIQATQNRVLQSLQPSPHDIEVVRRISSEAQRTPLRLSDLTNSLSPGEKDEIKRKLQMNQQLFTQVSNYAPQVYVFTKNENFLKEVLQLRIFVKEILEKCSKDIFVVKLDTVDKLVVKYQKYWESMKMQLIRRQQLVEQSKANHNQLKSQQQQQQQEQQQNPPISQQQQKVQGNLQQIQQQMQWQQQQQQAAQQQQQMSNSASANGTPSTASSVPLDASKHNYHQQIIANTMRSAGTGPGGNNNNNNSGTPSLAPVMEPPSTTGSVSPKKEPGQMKSAGRSKSVTKKISPAVVNQVIPSGMGQQGQQQTSNSTTPMVNNFIPGNSPAATATTITTAATTIAAGNGLSQNSPSPLSGPPTTTTAMTTSSGAIVANPFKEDEAKLADLNLKKNEMISRFKHRQEIYGNSKMDLFLLTLGDCLGINENEMEPIYQIPTTVVAHINGTGKKKITKAVQRVRDRDVVNVTIKDNKLIMKSKKLEPSPNANSSSTGKKSGIEKQENNILTRNYEINLNDISSIFKKVSGGNNLNDLFLNDNSNTPLNNSLIDNNHNEVENMRKRKFKEVDISPTNSDGSSASLMDDSKRIKVDSPDDVFSGKTDEDEEENADYSGSNHIKIKQEIDDDDHLHKEKSIKVDDRIWNWEFWEGLDTSRLPSGMS
Length1134
PositionTail
OrganismNaumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Naumovozyma.
Aromaticity0.04
Grand average of hydropathy-1.030
Instability index55.77
Isoelectric point9.54
Molecular weight127516.51
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
RNA polymerase II activating transcription factor binding	GO:0001102	IEA:EnsemblFungi
TFIIE-class transcription factor complex binding	GO:0001095	IEA:EnsemblFungi
TFIIH-class transcription factor complex binding	GO:0001097	IEA:EnsemblFungi
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of invasive growth in response to glucose limitation	GO:2000219	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi
regulation of establishment of protein localization to chromosome	GO:0070202	IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly	GO:0051123	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27684
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|    1081.26|     243|     245|     307|     551|       1
---------------------------------------------------------------------------
   97-  170 (54.72/ 9.86)	.........................................................................................................................................................................................IP..NP...NIS..NTN......TNANTN........NNNNiNMDP...QAFLNQQA.Q......ARQQ..AA..MQ.......LKNR..QQQQQQQQQQQQPQQRLTPQQ................QQLI........NQM
  175-  302 (164.99/44.83)	IP....................RELLQ.............K....IPNVP.....AGVTTW.QQ.....ITELAQQKIL..........SQDDMTVAKEMYK....LHQQllfksklQQQQQQQQLS...QQQQQR.QGQQGQG.qvlPPQQQQLqqqqqQLQQQQQ.Q..PRGTSVS....TNQNP..NQQRAR.............................................................................................................GQ.QPQQQQQ.............
  307-  551 (416.96/127.90)	IPNVLGQINEIFTT...E..EQRALLQ.............EAMEACKNYQKNQF.GNMTTVPEQaRQlFIRKYINQKVLK..KIQSVRLAQAAAMAATNNNKP...MPQQ.......QQQHQQQQQQ...QQQQTRVQATQNQG....PMQQAQI.....QLQPQQR.SGIPNATPSSAGYKSSQVP..TPQGNNIGGVNNN.....STNNNNN........NNNN.NMSTSRIQATQNRVL.Q......SLQP..SPHDIE.......VVRRISSEAQRTPLRLSDLTNSLSPGEK....DEIKR.KLQMNQQLFTQVSN.YAPQV
  553-  665 (94.31/22.58)	...VFTK.NENFLK...EvlQLRIFVK.............EILEKC...SKDIFvVKLDTV.DK....LVVKY..QKYWEsmKMQLIRRQQLVEQSKANHNQL...KSQQ.......QQQQQEQQQNppiSQQQQKV.....QG....NLQQIQQ.....QMQWQQQ................................................................................................................................................................
  666-  795 (101.43/24.56)	............................................................................................................QQ.......QAAQQQQQMS........................................nSASANGTPSTA....SSVPldASKHNYHQQIIANtmrsaGTGPGGN........NNNN.NSGTPSLAP....VM.EppsttgSVSPkkEPGQMKsagrsksVTKKIS......P....AVVNQVIPSG..............MGQQGQQQTSNsTTPMV
  820- 1071 (248.84/71.24)	AGNGLSQNSPSPLSgppT..TTTAMTTssgaivanpfkedEAKLADLNLKKNE....MISRFKH.RQ...EIYGNSKM....DLFLLTLGDCLGI.NENEMEPiyqIPTT.......VVAHINGTGK...KKITKAVQRVRDRDvvnvTIKDNKL.....IMKSKKL.EPSPNANSSSTGKKSG..I..EKQENNI..LTRN.....YEINLNDissifkkvSGGN.NLNDLFLNDNSNTPLnN......SLID..NNHN.E.......V.....ENMRKRKFKEVDISPTNSDGSSaslmDDSKRiKVDSPDDVF...........
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27684 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KANHNQLKSQQQQQQQEQQQNPPISQQQQKVQG
2) LQQIQQQMQWQQQQQQAAQQQQQMSNSASANGTPSTASSVPLDASKHNYHQQIIANTMRSAGTGPGGNNNNNNSGTPSLAPVMEPPSTTGSVSPKKEPGQMKSAGRSKSVTKKISPAVVNQVIPSGMGQQGQQQTSNSTTPMVNNFIPGNSPAATATTITTAATTIAAGNGLSQNSPSPLSGPPTTTTAMTTSSGAIV
3) LQVLMDINEINGGNSETASKMKVHAKNFENALYAKSSSRKEYLDSMREKVNAMRETRDSRKKAINSRSNDQNINYIPNPNISNTNTNANTNNNNNINMDPQAFLNQQAQARQQAAMQLKNRQQQQQQQQQQQQPQQRLTPQQQQLINQMK
4) NDLFLNDNSNTPLNNSLIDNNHNEVENMRKRKFKEVDISPTNSDGSSASLMDDSKRIKVDSPDDVFSGKTDEDEEENADYSGSNHIKIKQEIDDDDHLHK
5) QQQQLQQQQQQPRGTSVSTNQNPNQQRARGQQPQQQQQQQREI
6) VRLAQAAAMAATNNNKPMPQQQQQHQQQQQQQQQQTRVQATQNQGPMQQAQIQLQPQQRSGIPNATPSSAGYKSSQVPTPQGNNIGGVNNNSTNNNNNNNNNNMSTSRIQATQNRVLQSLQPSPHDIEVVRRISS
619
653
22
1006
265
372
651
850
171
1105
307
506










Molecular Recognition Features






MoRF SequenceStartStop




1) RIWNWEFWEGLDTSRL
1114
1129