<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27675

Description Uncharacterized protein
SequenceMQTSSESELSKLLTPKLTLDQLEDRLAGDIDNLDTTDLSDDSLPKQVIANSLIETEKSILPLRLVFNKLIQTMATLDTMPEKSQQEMFLSIRNQLLDLYTKIQEISTDFQHLQPLFGTIEEYSEKNNTKKFHMLETLKPIVEPAPATAKATKGDASHSKKKSVAGTPGSVGNTPVGTTPGSSTGTVAANVPANINANTTNTSTTSAASTTQTTSSTAKKPRKPRQNKKAAAKAQQQQQQQLLQQQQQQQIPKQQGIATNPMMNMNAMNATPMMNSVSPSNVMGTPLNNGISPMGAVMAGGFYSQPPGSQSQQFDQQMNNGDHNTNNNNFQNMNNITPANILSMNTVGDPQSRMASSSQQYPTNNNNNNTLDLNNLDLSSLNMDFL
Length385
PositionTail
OrganismNaumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Naumovozyma.
Aromaticity0.03
Grand average of hydropathy-0.692
Instability index46.24
Isoelectric point6.12
Molecular weight41820.28
Publications
PubMed=22123960

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
RNA polymerase II activating transcription factor binding	GO:0001102	IEA:EnsemblFungi
RNA polymerase II core promoter sequence-specific DNA binding	GO:0000979	IEA:EnsemblFungi
RNA polymerase II repressing transcription factor binding	GO:0001103	IEA:EnsemblFungi
transcription coactivator activity	GO:0003713	IEA:EnsemblFungi

GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly	GO:0051123	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27675
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.46|      54|      67|     223|     285|       1
---------------------------------------------------------------------------
  223-  285 (83.46/50.60)	PRQNKKAAAKAQQQQQQQlLQQQQQQQIPKQQGIATNPMMNMNamNATPM....MNSVspsnvmGTP
  292-  349 (98.00/41.75)	PMGAVMAGGFYSQPPGSQ.SQQFDQQMNNGDHNTNNNNFQNMN..NITPAnilsMNTV......GDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.85|      13|      16|      18|      33|       2
---------------------------------------------------------------------------
   18-   30 (21.16/19.38)	TLDQLEDRLAGDI
   35-   47 (21.69/ 9.16)	TTDLSDDSLPKQV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.76|      14|      16|      93|     106|       3
---------------------------------------------------------------------------
   93-  106 (23.23/17.08)	NQLLDLYTKIQEIS
  110-  123 (25.53/19.46)	QHLQPLFGTIEEYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.16|      30|      44|     145|     174|       5
---------------------------------------------------------------------------
  145-  174 (50.44/28.68)	PATAKATKGDASHSKKKSVAGTPGSVGNTP
  191-  220 (48.72/27.46)	PANINANTTNTSTTSAASTTQTTSSTAKKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27675 with Med3 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NTKKFHMLETLKPIVEPAPATAKATKGDASHSKKKSVAGTPGSVGNTPVGTTPGSSTGTVAANVPANINANTTNTSTTSAASTTQTTSSTAKKPRKPRQNKKAAAKAQQQQQQQLLQQQQQQQIPKQQGIATNPMMNMNAMNATPMMNSVSPSNVMGTPLNNGISPMGAVMAGGFYSQPPGSQSQQFDQQMNNGDHNTNNNNFQNMNNITPANILSMNTVGDPQSRMASSSQQYPTNNNNNNTLDLNNLD
127
376










Molecular Recognition Features






MoRF SequenceStartStop




NANANA