<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27670
Description |
Uncharacterized protein |
Sequence | MTDRLTQLQICLDQLVEQFCATLNYIDKNHGFEPLNTSEPLMSDKHATVAPPDEFSNTIDELSTDIILKTRQTMKLIDSLPGVDVSAEEQLHKIDSLQKKLVQVEEAKIQAIKEKENLLTQVDGLIDYFVTGIASTRHNNVGEVADSMTTPATTTTGTANTEMNTEVNTTDISINNATLPTNQNNVENTIQRLNTTEINVEK |
Length | 202 |
Position | Middle |
Organism | Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetaceae> Naumovozyma.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.451 |
Instability index | 25.31 |
Isoelectric point | 4.48 |
Molecular weight | 22417.79 |
Publications | PubMed=22123960
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | RNA polymerase II repressing transcription factor binding GO:0001103 IEA:EnsemblFungi
transcription coactivator activity GO:0003713 IEA:EnsemblFungi
transcription corepressor activity GO:0003714 IEA:EnsemblFungi
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP27670
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 59.65| 16| 16| 77| 92| 1
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59- 75 (18.09/11.06) IDEL.STDIilKTRQTMK
77- 92 (26.73/19.48) IDSLPGVDV..SAEEQLH
94- 106 (14.83/ 7.87) IDSLQKKLV..QVEE...
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 94.06| 23| 23| 152| 174| 2
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131- 149 (23.33/ 9.68) ....TGIASTRHNN..VGEVADSMT
152- 174 (39.43/20.69) ATTTTGTANTEMNT..EVNTTDISI
177- 200 (31.30/15.13) ATLPTNQNNVE.NTiqRLNTTEINV
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|