<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27657

Description Uncharacterized protein
SequenceMSNQASLEKLNQTVEILSVRLAELIRLSSIENPSSMDDDDDNIDIQDSNLAIATSSTMMVNSHTMQLIRGVQDLLALTRNMREKWLLNQIPEQNQRQEDTNSKVDHEELATILEKTMQEIVNEHTPSQ
Length128
PositionHead
OrganismNaumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Naumovozyma.
Aromaticity0.01
Grand average of hydropathy-0.607
Instability index40.40
Isoelectric point4.44
Molecular weight14589.14
Publications
PubMed=22123960

Function

Annotated function
GO - Cellular Component
core mediator complex	GO:0070847	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27657
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.44|      36|      58|      27|      64|       1
---------------------------------------------------------------------------
   27-   64 (57.41/38.83)	LSSI.ENPSSMDDDDDNIDIQDsnLAIATSSTM..MVNSHT
   87-  125 (52.03/29.47)	LNQIpEQNQRQEDTNSKVDHEE..LATILEKTMqeIVNEHT
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27657 with Med22 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LLNQIPEQNQRQEDTNSKVDHEELATILEKTMQEIVNEHTPSQ
86
128

Molecular Recognition Features

MoRF SequenceStartStop
1) DNIDIQDSNLAIAT
2) KVDHEELA
3) LLALTRNMREKWLLNQIPEQNQRQ
4) LSVRLAELIRLSSIENPSSM
5) TMQEIVNEH
41
103
74
17
116
54
110
97
36
124