Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MPSNDANDVSSLYPPPPPYIKFFTQQNVDKLEKYKEEKQLTEANDENDPTVVEGDSEEVFTNELDYLIPPKMPKSHQYRAFGSVWQVKDQLPDLESMGITQLYKKSDEIGKPTNYQYKIQESRKLLKSLLLNYLELIGVLSINPEIYQQKVENIRTILINIHHLLNEYRPHQSRESLIMLLEEQLEYKKREIKHIEQTCDHVREKLSKISDPKSLD |
Length | 216 |
Position | Middle |
Organism | Naumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Naumovozyma. |
Aromaticity | 0.08 |
Grand average of hydropathy | -0.809 |
Instability index | 47.64 |
Isoelectric point | 5.37 |
Molecular weight | 25403.54 |
Publications | PubMed=22123960 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060 |
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi |
Binary Interactions |
Repeats | >MDP27652 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 76.00| 20| 50| 116| 135| 1 --------------------------------------------------------------------------- 116- 135 (32.73/23.53) QYKIQESRKLLKSL..LLNYLE 148- 166 (15.95/ 7.90) QQKVENIRTILINIhhLLN... 168- 186 (27.33/18.50) .YRPHQSRESLIML..LEEQLE --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) DVSSLYP 2) PPPYIKFFTQQNVD | 8 16 | 14 29 |
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