<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27634

Description Uncharacterized protein
SequenceMENLWRAPPLSQQRSAAGFRGTTGAKPATYGADSHLPWPVPGLRSSVTTTGSSTAVAGQMHQLHAAASAAAGFSFMPFFAAGFGTDSEVITAGGMSQGGRRNRADAFQSRPYPDRRPMGYQSKVRVTDKYKVIGFISSGTYGRVYKALGRQGQPGEFAIKKFKPDKEGEQATYTGISQSAIREMALCSELSHPNIIKLIEIILEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPSTIKSIMFQLLNGCQYLHSNWVLHRDLKPANIMVTSAGEVKIGDLGLARLSYKPLHSLYSGDKVVVTIWYRAPELLLGSRHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGLPTKERWPLLTSTPEYSQLATLTPPVSHSHHHHHHHSHHYNSQQQRNLGSTSHLEKWYYTTISPPSHSQGPSPLSSLGAEGYSLLSGLLEYDPEKRLTATQALQHPFFSTGDPVNATNCFEGSKTEYPVRRVSQDDSLSGLGGGDRSGGLTGVKRSLGGEAGGGGGKRVKEG
Length541
PositionKinase
OrganismChaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Sordariales> Chaetomiaceae> Chaetomium.
Aromaticity0.09
Grand average of hydropathy-0.430
Instability index47.89
Isoelectric point9.28
Molecular weight59397.64
Publications
PubMed=21784248

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27634
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.19|      21|      48|      99|     121|       2
---------------------------------------------------------------------------
   99-  121 (35.51/26.67)	GRRNRADAFQSRPY.PDRRpmGYQ
  149-  170 (34.68/18.90)	GRQGQPGEFAIKKFkPDKE..GEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.28|      18|      52|      16|      34|       3
---------------------------------------------------------------------------
   21-   73 (15.38/ 6.80)	GTTGAKPATYGADShlpwpvpglrssvtttgsstavagqmhqlhaaasaAAGF
   74-   95 (28.90/12.83)	SFMPFFAAGFGTDS...............................evitAGGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.60|      11|      16|     506|     518|       4
---------------------------------------------------------------------------
  506-  518 (17.15/12.69)	SLSGLGGGdrSGG
  525-  535 (22.45/10.11)	SLGGEAGG..GGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      51.99|      12|      47|     286|     299|       6
---------------------------------------------------------------------------
  286-  299 (16.37/14.73)	LSYK.PlhSLYSGDK
  304-  316 (17.34/ 7.95)	IWYRaP..ELLLGSR
  335-  345 (18.28/ 8.77)	LSLR.P...IFKGEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27634 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NCFEGSKTEYPVRRVSQDDSLSGLGGGDRSGGLTGVKRSLGGEAGGGGGKRVKEG
487
541










Molecular Recognition Features






MoRF SequenceStartStop




1) EKWYYTTI
2) GGLTGVKRSLGGEAGGGGGKRVKEG
424
517
431
541