<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27621

Description Predicted protein
SequenceMVSFSCEACGDVLTKKKLDPHRSRCRGATFTCIDCMVYFPGFEYRSHTTCMTEEQKYQGALYKPKQNKKQQPQQQQQQQQQQQQQQKPAMNSHRMGMANTLALQPFVEDVNEDKEYESWHEYEVRDKSAAGPPPEAPTPPSAADDDHVNVFDFLDNSQTPTASNVSRTRERKPSNADDNTSLVRYETKTGELLEPASLMDQDGEPLVQYGTGPVPTADFVTPKPKTERRRSKDRDAQKDKKRKRLHIDVAGDQIMADAPPVLHSGLTGGLKNMMRPTLPPSPDYSGDNIADLSPASPVKKSKHSRHHKSHHHHHHQQSSTSIFGLIAGAPPKTKSSKRKSSSKKHSHKHDKKSPKLIEYRPGSKDGKGDHDGQMVVFKPRADVFLSFVKGPESERGCSMNKALKRFHRERQAAGDNIPKIKEEKELWRSLRLRRNDRGEIVLFCEE
Length446
PositionTail
OrganismHypocrea jecorina (strain QM6a) (Trichoderma reesei)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Hypocreaceae> Trichoderma.
Aromaticity0.06
Grand average of hydropathy-1.118
Instability index59.24
Isoelectric point9.28
Molecular weight50489.14
Publications
PubMed=18454138

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-KW

GO - Biological Function
DNA binding	GO:0003677	IEA:InterPro
metal ion binding	GO:0046872	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27621
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.18|      28|      34|     289|     318|       1
---------------------------------------------------------------------------
  289-  318 (47.65/25.23)	IADLSPASpvKKSKHSRHHKSHHHHHHQQS
  326-  353 (49.53/21.30)	IAGAPPKT..KSSKRKSSSKKHSHKHDKKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     125.32|      50|     160|     191|     254|       2
---------------------------------------------------------------------------
  191-  204 ( 6.85/ 7.45)	..................................................ELLEPASLMDQD.GE
  215-  254 (48.67/27.11)	PTAD.FVTPKPKTErrrsKDRDAQKDKKRKRLHID..VAGDQI......................
  379-  439 (69.79/29.58)	PRADvFLSFVKGPE....SERGCSMNKALKRFHRErqAAGDNIpkikeekELWRSLRLRRNDrGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.29|      15|      15|      31|      45|       3
---------------------------------------------------------------------------
   31-   45 (30.77/19.32)	TCIDCMVYFPGFEYR
   49-   63 (27.53/16.64)	TCMTEEQKYQGALYK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27621 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EDKEYESWHEYEVRDKSAAGPPPEAPTPPSAADDDHVNVFDFLDNSQTPTASNVSRTRERKPSNADDNTSLVRYETKTGELLEPASLMDQDGEPLVQYGTGPVPTADFVTPKPKTERRRSKDRDAQKDKKRKRLHIDVAGDQIMADAPPVLHSGLTGGLKNMMRPTLPPSPDYSGDNIADLSPASPVKKSKHSRHHKSHHHHHHQQSSTSIFGLIAGAPPKTKSSKRKSSSKKHSHKHDKKSPKLIEYRPGSKDGKGDHDGQMV
2) QKYQGALYKPKQNKKQQPQQQQQQQQQQQQQQKPAMNSHRMGMANTLALQPFVEDV
112
55
375
110










Molecular Recognition Features






MoRF SequenceStartStop




1) IFGLIA
2) KKRKRLHIDV
3) KRKSSSKKHSHKHDKKSPKLIEYRP
322
240
337
327
249
361