<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27602

Description Uncharacterized protein
SequenceMDVLEKVKTAIVKYEVQNRVNCYVYKDLERNQIFYFQLHMDRDSYEIALKGRRPRLHRREMERADQRLESNICLTFSAITEPADKIVDSIQDSLRDKMEDLLLSEIMRGYSQNQEQPLMLNEIRFLQPLYRGPVVRKFFSIPFIFEEYLSSLLFYIGQHLEELSSISPGKVKESGFFYNGAVFNRTPVDSTAIGRRKSFRTRWEPIKVELKEFKETTDENGIDVGIEAKEGILRQFSLEEKERVAQQKEKALQMELEKENLPQPRHPGAVFRAYKPIAGEMPSNYLLSSFFIYHILPARGVVDTGIALIEFRITKPDGRLIAKFDQPSMNEQSHNLLVPNVPDDKALVYRDIIKSHTSSAPNPEKEKNICGYVDMIVHTRGVVVEDVFEKMMYEMIEMSMFDVITEFGYLNTTIVEEGVLTGHVAYTNRNSEVFLPSQDSTENPPVKHLTKQGSASSVTASVDTRHTHAAPSHSGEIRRSLVQPMSVPPQHAPRPASVAHPASIPANIHVIGSPPSNQMDQMGGQSQYPMHLLAQKILSRSGSQQGQHNSGMGRAQKRERTTHSYNLRSSRASTSEVGSNSQAVGGADDGGSDSDDDNGRNRKKVKVGDNVDNSDDDDASDEEEVDDEENEDDDMEAEQNEANIKSFGDSDDDNDMEDGEEGDDEMEDEEDDDDEEEEEARCQRVEEEEDDEDDDEDEDEDQEPPFHYDDEDDDYYYINLVSPNTSSSSSSSSSTDSSRSSSSASSSGSSTSSEESDRELPEEEPEEDDPAEEEEDPAEEDDDQENDNMNGPRPRNHVGRREVFGENNENQRKNVSESESSFVASSDEDDGYKKKKKKSKMETKPKKTRRGRDDEDEDTAMNILQDGIRQSRRLAGEDADLEREATPEEYNGWFAKDKLVTDDDRDDFTLSNKLVLLMEIINKCEEIGDKLLVFSQSLESLALIKRMLEYMAGTGQWFADGHEALNAEGETWSWLEGEDYMTIDGSVQSVKRDAVQTTFNDPENMMARLMLISTRAGSLGTNMVAANRVIIFDACWNPSHDTQSLLRVYRFGQTKPVYIYRFIAQGTMEERIYKRQVTKESTSMRVVDEAQIQRHYLGNDLTELYQFTQSIYDPDVEIACAPPKDRLLADVIHQNQAAVVDYIERDTLFANQEEEKLSEQEMKDAWADYEKDKSGVPMDRVPYHLGVRPQGIIVEQQMQAILQNRALETQRLDQIQNDVLFKELNKMRHKDIPTFLKIILLRNLLEQVLPFIPDEMRGGMTEFNTHFIRLVHESDRKQETAAELLRKSLESFKTVIRMIRTIPTCKAPLDRIAMQHPYLFQDN
Length1323
PositionTail
OrganismCaenorhabditis brenneri (Nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.07
Grand average of hydropathy-0.823
Instability index55.33
Isoelectric point4.65
Molecular weight151058.37
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
ATPase activity	GO:0016887	IEA:InterPro
DNA binding	GO:0003677	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27602
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.70|      20|      20|     664|     683|       1
---------------------------------------------------------------------------
  655-  673 (22.81/ 7.23)	DMEDGE...EgdDEMEDEED....DD
  674-  695 (27.55/10.36)	DEEEEEARCQrvEEEEDDED....DD
  759-  782 (22.34/ 6.92)	ELPEEEPEED..DPAEEEEDpaeeDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     104.30|      14|      16|     726|     739|       2
---------------------------------------------------------------------------
  539-  554 (18.04/ 7.13)	SRSGSQQGQHNSGmgR
  568-  581 (18.96/ 7.88)	RSSRASTSEVGSN..S
  587-  600 (21.00/ 9.56)	ADDGGSDSDDDNG..R
  726-  739 (22.36/10.68)	SSSSSSSSSTDSS..R
  745-  758 (23.95/11.98)	SSSGSSTSSEESD..R
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.16|      16|      16|     480|     495|       4
---------------------------------------------------------------------------
  480-  491 (17.58/ 8.50)	.....SLVQPM...SVPPQ.H
  492-  509 (19.96/10.91)	APRPaSVAHPA...SIPANiH
  513-  531 (25.61/16.64)	SPPS.NQMDQMggqSQYPM.H
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.33|      18|      20|     339|     357|       5
---------------------------------------------------------------------------
  339-  357 (29.49/28.24)	PNVPDDKALV.YRDIIkSHT
  361-  379 (30.84/23.63)	PNPEKEKNICgYVDMI.VHT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     244.37|      68|      80|     874|     941|       6
---------------------------------------------------------------------------
  805-  872 (38.50/18.35)	..GEN...NENQRKNVSESESSFVAssdeddgykkkkkKSKMETkpkktrrgrDD..EDEDTAMN....ILQDGIRQSR................
  874-  941 (111.32/67.43)	LAGED...ADLEREATPEEYNGWFA.............KDKLVT.........DD..DRDDFTLSNKLVLLMEIINKCEEIGDKLLVFSQSLESL
  951- 1019 (94.54/56.12)	MAGTGqwfAD.GHEALNAEGETW................SWLEG.........EDymTIDGSVQSVKRDAVQTTFNDPENMMARLMLISTRAGSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.00|      16|      18|     229|     246|       7
---------------------------------------------------------------------------
  229-  246 (18.70/21.25)	KEGILrQFSLeEKERVAQ
  248-  263 (28.30/18.72)	KEKAL.QMEL.EKENLPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.55|      21|      35|     126|     146|       9
---------------------------------------------------------------------------
  126-  146 (38.53/29.18)	LQPLYRGPVVRK.FFSIPFIFE
  163-  184 (32.02/22.86)	LSSISPGKVKESgFFYNGAVFN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.60|      34|     232|      69|     102|      12
---------------------------------------------------------------------------
   69-  102 (56.14/36.60)	ESNICLTFSAITEPADKIVDSI.QDSLRDKMEDLL
  303-  337 (53.46/34.49)	DTGIALIEFRITKPDGRLIAKFdQPSMNEQSHNLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27602 with Med29 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NSEVFLPSQDSTENPPVKHLTKQGSASSVTASVDTRHTHAAPSHSGEIRRSLVQPMSVPPQHAPRPASVAHPASIPANIHVIGSPPSNQMDQMGGQSQYPMHLLAQKILSRSGSQQGQHNSGMGRAQKRERTTHSYNLRSSRASTSEVGSNSQAVGGADDGGSDSDDDNGRNRKKVKVGDNVDNSDDDDASDEEEVDDEENEDDDMEAEQNEANIKSFGDSDDDNDMEDGEEGDDEMEDEEDDDDEEEEEARCQRVEEEEDDEDDDEDEDEDQEPPFHYDDEDDDYYYINLVSPNTSSSSSSSSSTDSSRSSSSASSSGSSTSSEESDRELPEEEPEEDDPAEEEEDPAEEDDDQENDNMNGPRPRNHVGRREVFGENNENQRKNVSESESSFVASSDEDDGYKKKKKKSKMETKPKKTRRGRDDEDEDTAMNILQDGIRQSRRLAGEDADLEREATP
430
887










Molecular Recognition Features






MoRF SequenceStartStop




1) DQEPPFHYDDEDDDYYYINLVSPNTS
2) HLLAQKIL
3) RELPEEEP
4) YKKKKKKS
701
531
758
832
726
538
765
839