<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27582

Description Uncharacterized protein
SequenceMESSRDMSFAVPEPLVKKNSETQNKDGEPSSTEEASTAPTCSERTENTGRDPKVSLFSSFANALMGTKVMLGSAPFGYGEKSYPFEIGSGAPSVSSLFRSASSNSLTSSASGVSSKLFEFGAPSCSTQSGSGAPNSSTQSETPTSSTLAGSEAPRSSDKSGSEAPNSSSAGPGALKDSSKSKSGEPNTSTSVGPEAPSNSAPAGSGETNKSTQSGTEAPNTTSTTVPVEIQANVSKNTDDSSEKDKQPENPPPNSTVAVAQKKGTGNTKTVDCCQQMLNLLHELRRTAKIFRKETHKFTGSSREHKLLIEKLNRRLIAIMNKMTEKCKDLPEEVPKFQEMEMMDIFHEEGPRGLDFQIKMDAIEDKSNWWEGEYHHIHFYTEFMPFYKVARPARIPRSPNVPIPRDPKTPTAQQRHRNFLLLYSAVKATVTPWSFGFVSDVLSFTHNTSFIEFKIVEKSCPKVCIMKILILERLGDIGYITIAAPNQRWDKEANDYGPPKLAPFTAAVHKVYEKFTVDANVKLQERYDMIENLTRERFLWFIWLFAQYRTLFRAKCYGCKKILHNFMPPTTFDKTGKPFHEPCMNRILSVPGMFQGCSS
Length599
PositionTail
OrganismCaenorhabditis brenneri (Nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.08
Grand average of hydropathy-0.595
Instability index51.75
Isoelectric point8.46
Molecular weight66066.70
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27582
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     180.14|      28|      30|     161|     188|       1
---------------------------------------------------------------------------
   36-   83 (22.49/ 8.09)	.STAP.TCSE........RTENTGRDpkvslfssfanalmgtkvmlgS.APFGYGEKSY
   88-  116 (34.18/16.51)	GSGAP.SVSS........LFRSASSN.....................SlTSSASGVSSK
  161-  188 (50.81/28.50)	GSEAP.NSSS........AGPGALKD.....................S.SKSKSGEPNT
  193-  210 (26.74/11.15)	GPEAPsNSAP........AG.................................SGETNK
  215-  249 (26.20/10.77)	GTEAP.NTTSttvpveiqANVSKNTD.....................D.SSEKDKQPE.
  251-  268 (19.73/ 6.10)	...PP.PNST........VAVA.............................QKKGTGNT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     196.07|      57|     184|     336|     396|       2
---------------------------------------------------------------------------
  336-  396 (96.61/84.63)	KFQEM.EMMDIFHEEgpRGLDFqIKMDAiEDKSNWWEGEYHHIHFYTEFMP...FYKVARPARIP
  522-  582 (99.46/69.85)	KLQERyDMIENLTRE..RFLWF.IWLFA.QYRTLFRAKCYGCKKILHNFMPpttFDKTGKPFHEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.63|      18|      28|     280|     297|       3
---------------------------------------------------------------------------
  280-  297 (31.06/27.37)	LLHEL.RRTAKIFRKETHK
  308-  326 (25.57/21.12)	LIEKLnRRLIAIMNKMTEK
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27582 with Med27 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LFEFGAPSCSTQSGSGAPNSSTQSETPTSSTLAGSEAPRSSDKSGSEAPNSSSAGPGALKDSSKSKSGEPNTSTSVGPEAPSNSAPAGSGETNKSTQSGTEAPNTTSTTVPVEIQANVSKNTDDSSEKDKQPENPPPNSTVAVAQKKGTGNTKTVDCCQQ
2) MESSRDMSFAVPEPLVKKNSETQNKDGEPSSTEEASTAPTCSERTENTGRDPKVSLF
117
1
276
57

Molecular Recognition Features

MoRF SequenceStartStop
1) MESSRDMSFAVPEPLVKKNSETQ
1
23