<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27581

Description Uncharacterized protein
SequenceMSEAGPSIEEPIEMDDTFAPQFVREVNQLKNHIKKVVEETDTRKFFRSVTSNLGDNTAFLRVSFNNMIGKMEEKEKQSLIKELIKMVHHVAEKNSPDRIFVGANYERVVDQLLRYAHQKGTISTNLCAEGLIMTSDFRMCSRIDQEKWKFIKDCIPKIDYKGIRNILRYILESQLRRLPFALSPEQVNELRIVEDVVLQIVDRDNNLMPPLITLSEVMRGMPKQALMLPRLTEKVANISVHFRPIADLTHVCGRAYVYPIAFHPTFFPQTSYWEDFGLNVISAYVQAHHTLPYRPEHTSNLLYTLYMILKQPLGKDSFQSSSKSKYKSHWDVMISVMICEAMAETESLPENEPIPRYQWDNIVNIVIHGMASHLLNPKNFFHVLKDLIKQCKYTRARDEVMWIVFQVVGSLNNVVRLDESVQEIVDLYNELFEGNVVWMGASDHPALFARFLAAACTWMILEREYPDKMPPANDTIKSHMQVIRDGAENIDSSNTAMVAVVSNAYRNDSKIMKEVLISLSELIDKPNPSQPTFELSYGRTAINSFDGFPLELMDALSLRSKKSLLAHTTNCLRTFTTGRLLDYENAAKDVESLALRSLHVALAYDRTQDNQSLFGTNCNKDNVLMRHLSQPKTLLSSSRSISIPSESRAIQNDIVLISTIELTLPYSIRWLWVAREIHVILPEMGSRSHEKKDPSTIFTRNPEEILNVVRDIILCQKGLTPNQFVSRYGDDADPTTMYCMMAVVFRFAYVSLDSKPDITSEYYEVMEKKSPKDIVLMGNYLIDYIIADMKTQDINEQTFKNIAKAAAILIFQYQILRADRFLLSLIMHPGTDEDALLCVQIANEFILTQEFQERIRWFHQNVPKKDQYPTEFIKSIVKYHDNFPEFEACELVRKYDSSANPHMPTYYGCLIERLLPILDQYVYVALEQQGYKLNPQILQTLALFYKYHAQPIHFMYSVLYISHGKMSGPDAKSFVMSFAAQIEECHLTEAFEKFNHQKTSTEQLIMDLIDRITASVDFVLTPPSFVAKDWKMAELAPGAQTLYLACIELMASPHSPETLVSAMINVMQMKPHLRPFNVINCIALILTALPSSYSEALHNELVAVFDNGDTAKLKFEELVFDIYEENLLLNIPSRVKSLNVISQFYFIHCNMSILNYFPQIYVPKLLEHIKTENDLWYGLRIMMPVVRRYWENWDNRKQMRSQKMKFGPLNVMRLIFEKLGSMGEAGVEFDHDAHLCDLFYNCKYVFTGDFLRDTAIAEFAKLPEKMRDRLKFYVSQSEPQQEDHKEKTPEKEEKEEKEKDPEPAAPVAQQQQQQQQHQMAAAAMHQQMTPQYPAPMFHHQSPAHHMPYGMTSHMQQAMQQHAAHQQMVQGQMHMNPMMHNMTPQQQQQQYAYMQFLHQQQQQHQQQQQQQQQPPHM
Length1416
PositionTail
OrganismCaenorhabditis brenneri (Nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.10
Grand average of hydropathy-0.328
Instability index53.86
Isoelectric point6.07
Molecular weight163969.77
Publications









Function






Annotated function


	RuleBase:RU364150

GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP27581
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.02|      16|      92|    1309|    1324|       1
---------------------------------------------------------------------------
 1303- 1319 (29.07/12.65)	PAAPV.....aQQQQQQQ......QHQM
 1320- 1341 (19.52/ 6.28)	AAAAM......HQQMTPQypapmfHHQS
 1373- 1393 (20.43/ 6.89)	HMNPMmhnmtpQQQQQQY......AY.M
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.20|      39|      82|     264|     311|       2
---------------------------------------------------------------------------
  264-  311 (57.03/67.54)	PTFFPQTSY.WEdfglNVISAYVQ..AHHTLpyRPEhtsNLLYTLYMILKQ
  349-  390 (63.16/43.83)	PENEPIPRYqWD....NIVNIVIHgmASHLL..NPK...NFFHVLKDLIKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.77|      22|      70|    1076|    1097|       5
---------------------------------------------------------------------------
 1046- 1059 (19.69/ 7.86)	.....CIELM..ASPHS.PETL
 1076- 1097 (37.40/21.64)	FNVINCIALILTALPSSYSEAL
 1144- 1165 (39.68/23.41)	FYFIHCNMSILNYFPQIYVPKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.57|      34|      70|      49|      84|       6
---------------------------------------------------------------------------
   49-   84 (46.66/37.60)	VTSNLGDNTAFLRVSFnNMIGKMeEKEKQSLIKELI
  122-  155 (61.91/39.80)	ISTNLCAEGLIMTSDF.RMCSRI.DQEKWKFIKDCI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     166.10|      37|      37|     658|     694|       7
---------------------------------------------------------------------------
  658-  694 (66.04/45.76)	STIELTLPYSIRWLWVAREIHV....ILP.EMGSRSH...EKKDP
  695-  734 (48.37/31.37)	STIFTRNPEEI..LNVVRDIILcqkgLTPnQFVSRYG...DDADP
  735-  771 (51.69/34.07)	TTMYCMMAVVFRFAYVSLDSK.......P.DITSEYYevmEKKSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.22|      49|     810|     399|     451|      11
---------------------------------------------------------------------------
  399-  451 (76.88/62.86)	EVMWIVFQVVGSLNNV.VRLDESvQEIVDLYnelFEGNVVWMGASDHPALFARF
 1210- 1259 (83.33/55.50)	NVMRLIFEKLGSMGEAgVEFDHD.AHLCDLF...YNCKYVFTGDFLRDTAIAEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.38|      11|      36|    1359|    1371|      12
---------------------------------------------------------------------------
 1345- 1364 (10.69/ 9.19)	HMpYGMtshmqqamQQHAAH
 1405- 1415 (22.69/ 8.13)	QQ.QQQ........QQQPPH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.94|      29|     302|     196|     224|      13
---------------------------------------------------------------------------
  196-  224 (51.45/34.68)	VVLQIVDRDNNLMPP.LITLSEVM.RGMPKQ
  500-  530 (40.49/25.63)	VVSNAYRNDSKIMKEvLISLSELIdKPNPSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.02|      15|      18|     850|     866|      14
---------------------------------------------------------------------------
  850-  864 (29.99/22.65)	EFQERIRWFHQNVPK
  871-  885 (28.03/13.18)	EFIKSIVKYHDNFPE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27581 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LKFYVSQSEPQQEDHKEKTPEKEEKEEKEKDPEPAAPVAQQQQQQQQHQMAAAAMHQQMTPQYPAPMFHHQSPAHHMPYGMTSHMQQAMQQHAAHQQMVQGQMHMNPMMHNMTPQQQQQQYAYMQFLHQQQQQHQQQQQQQQQPPHM
1270
1416










Molecular Recognition Features






MoRF SequenceStartStop




NANANA