<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27580

Description CBN-MDT-17 protein
SequenceMESGSAGPSTPQEPMELDEAGPSEPQAPESSAIRKGVELVLEANDDWKIQEIGFDGVERYLKPETFTDHVRKLARKVEWMKLVDSKTPYENAKVEPDEEEDERLQEVGKHGTNVELVSPEAGPWSSVAKYLHESLNQVNILLDDLSVMKNTEYMKALTVLDPIIVQEPTAEFINTNRGTQWIWKRRALQEAVQVLDTALKQRQRALSNLGLSADYIAHLQRTKFFEELKEMREVWRVRKSGDYIYGDLSYHIFGWKYDAHLLFDISRRTLSSKFETSDLSIIEVSVPKDLARRSMLCVSIVKDDVDSGYLFRDPDDTKYTYAYKEADADKIKDLHWKDSLKWAQNTLLLRDTFHTLCKDAIKLRNRLSVIRDNVLLIQLFDDYLLKIELQHFQFQPGEIKEEGDIYLNRILRELMIAFECKKFIRPQFFCSMAVTHLPENLDLRGCGGFSTKEIEDRAVRPQSILDRLLEMAGHRALVNMMTDIAERVSRGRRDPTISYKWLTCGRHASSMMFQLTSKDYEQFMGNSVRNVFFTRVTFDSIEVHTKDGQVMKCDRDPARILYSCQYVICCYSLSIVSIISRNPWQTPFQTLYANTSALDEKGNPAPSIVLCNQGATRAISFAFRVGAEPEIKVRRFVVNEKTAKPEEHQWKKLSYSRLYGNTLSKKVDTLLSFLRDC
Length677
PositionHead
OrganismCaenorhabditis brenneri (Nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.09
Grand average of hydropathy-0.442
Instability index37.51
Isoelectric point6.14
Molecular weight78124.29
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27580
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.72|      12|      17|     235|     251|       3
---------------------------------------------------------------------------
  235-  249 (18.47/20.96)	WrvrKSGDYIYGDLS
  255-  266 (23.25/ 8.44)	W...KYDAHLLFDIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.08|      14|      17|     140|     154|       6
---------------------------------------------------------------------------
  140-  154 (20.05/19.06)	IlLDDLSVMKNT.EYM
  159-  173 (20.03/12.97)	V.LDPIIVQEPTaEFI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27580 with Med17 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MESGSAGPSTPQEPMELDEAGPSEPQAPESSAIRKGV
1
37










Molecular Recognition Features






MoRF SequenceStartStop




1) EPMEL
13
17