<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27576

Description CBN-MDT-29 protein
SequenceMSGQGQQPMNQQQMMHHHQQLLRQQQMQSQQQGMNQRQMQHPQAQQQYQRARTPQMHQHPSGGSPGGSHLQMHPHLQPQGHMQPRSPLVGSQLQAPGSVTASNPATPQMMQQQIGMNQPMSVPPQHTPRPASVAPPASVPANIHVIGGPPSNQMDQMGGQSQYPMHLQAQQIPSRPGSQQGQHNLGHGGPQSVQQPGSIQRPGSVLAPGSIQPPGSQGGPQSHSGMGGPLSHSTIGNPQSVQAFGPGSVQQPGSAQAPSSVQPGSAFAPGSIQAPASQQPPASIQPPPSTSSAAAAATTQNNKEPLKPNEEQIRMVQDPVDLVRNLVQKDLRNCLVEMNKRGAVLVKKRFEGDSVLDEDKEQYKRSANDFDAVCDDVDRMLTTIMETAKQLSKLEKVFNERTLRDQDGEVMVNQVQTFVDNTDIVQKMFDDTINNVTATMEKVRRREKKWEDLQKEQQQIKEGVEDIDMEE
Length471
PositionTail
OrganismCaenorhabditis brenneri (Nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.02
Grand average of hydropathy-0.916
Instability index71.32
Isoelectric point6.63
Molecular weight51431.89
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
lateral inhibition	GO:0046331	IEA:EnsemblMetazoa
positive regulation of Notch signaling pathway	GO:0045747	IEA:EnsemblMetazoa
regulation of cell fate specification	GO:0042659	IEA:EnsemblMetazoa









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27576
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     315.28|      47|      47|     176|     222|       1
---------------------------------------------------------------------------
   28-   64 (53.00/11.47)	QSQQQGmnQRQM...QH.....PQAQQQ..Y...QRART...PQMHQ........HP.S..G....GS...
   65-  106 (56.85/12.80)	PG...G..SH.LqmhPH...LQPQ.......GHMQ.PRSPLVGSQLQ........APGSvtA....SNPAT
  107-  161 (65.95/15.97)	P..QMM..QQQI...GM...NQPMSV.P..PQHTPRPASVAPPASVPanihviggPPSN..QmdqmGG.QS
  176-  222 (98.57/27.32)	PGSQQG..QHNL...GH...GGPQSVQQ..PGSIQRPGSVLAPGSIQ........PPGS..Q....GGPQS
  226-  262 (40.91/ 7.26)	MGGP.......L...SHstiGNPQSVQAfgPGSVQQPGSAQAPSSVQ........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     156.56|      44|      47|     340|     386|       2
---------------------------------------------------------------------------
  300-  329 (35.00/18.94)	...................QNNKE....PLKPNEEQIRMV...QDPVDLVRNLVQK
  340-  386 (67.75/52.95)	KRgavLVK..KRFEGDSVLDEDKE....QYKRSANDFDAV...CDDVDRMLTTIME
  389-  441 (53.82/34.28)	KQ...LSKleKVFNERTLRDQDGEvmvnQVQTFVDNTDIVqkmFDDTINNVTATME
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27576 with Med29 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSGQGQQPMNQQQMMHHHQQLLRQQQMQSQQQGMNQRQMQHPQAQQQYQRARTPQMHQHPSGGSPGGSHLQMHPHLQPQGHMQPRSPLVGSQLQAPGSVTASNPATPQMMQQQIGMNQPMSVPPQHTPRPASVAPPASVPANIHVIGGPPSNQMDQMGGQSQYPMHLQAQQIPSRPGSQQGQHNLGHGGPQSVQQPGSIQRPGSVLAPGSIQPPGSQGGPQSHSGMGGPLSHSTIGNPQSVQAFGPGSVQQPGSAQAPSSVQPGSAFAPGSIQAPASQQPPASIQPPPSTSSAAAAATTQNNKEPLKPNEEQIRMVQDPVD
1
321










Molecular Recognition Features






MoRF SequenceStartStop




1) QYPMHLQAQQIP
2) YQRARTPQMHQH
162
48
173
59