<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27568

Description Uncharacterized protein
SequenceMHELVSFSQLPALREAQVLNILAGVTGTQPVDICEQRLIFAQVKVPEVAISKKQAQTKQQPQQSKRPSYEQLVRSLQLSQNKSTFTTPQESKSIPWHLRTEQTPSASTTATRPGQTAAPYIVREVALTPATPQILLRLTTPSLYAYKYQYILLGHRFVHGNIVIRVYRLYYASSASEGNASGEEAVEASPPQRQDLKPVDESGSWIVDATVRVEEGAGAEVLERGKRELERFRQGMEGCVDLKAGDRLSLDVRREGDRGSDRKLQIVQTGKVLLAQQCSDLGLRTRARRTWASPRMTFLPSLREVSHETFEDKQRREYEHSLTMAADTSMDVDMDFELDMDNDEELARLQAGTAALSALPSALQPDNDTDAMMTVEDGELQDGGQEILPHKIHISGLETLQTQDIENFTHDHFPSESHVKIEWVNDSSANIVYASGDIAAAALKAFALTPTDDPLEPRRAQQLLTHPDVDLYVRLAVATDVKPVGASKYSKFYLNNPELDPESRPRRGGLRGRGRGNGYRRGGGYQDDRYDRPRRRRSSTIEPTFDVNLYDDDPASIKARITPTAPSSDRSRRPRNGEDLFANRAPRNHSATSRRSSSDLLPNSRPDGRLRNRSASPVRDGDGRYGFTEDQPYRQTARHRTPPPARPRSTAENYGARAELRADLFAHRRTGSELAPGGRVRSPPPSRKAPIELFANKGSTAPAVKELFPDKAGHRRQEAKDIRAEEVVSAIGRFDMSDERDSYGRNGGSRNSGQRNGGDLMAKNRGRVNQNGRLTEENGGDDGFQIRGRGSSGFSILGASKSAMPPPDLFDRRAREGVRGGRG
Length823
PositionHead
OrganismZymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Zymoseptoria.
Aromaticity0.06
Grand average of hydropathy-0.818
Instability index59.67
Isoelectric point9.15
Molecular weight91389.57
Publications
PubMed=21695235

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
mRNA binding	GO:0003729	IEA:InterPro
RNA 7-methylguanosine cap binding	GO:0000340	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27568
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.05|      24|      24|     736|     759|       1
---------------------------------------------------------------------------
  581-  599 (28.96/11.40)	FA.NRAP..RNHSA..TSRRSSSD
  736-  759 (44.60/21.83)	MSDERDSYGRNGGSRNSGQRNGGD
  761-  781 (36.49/16.42)	MAKNRGRVNQNG..RLT.EENGGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.73|      22|      24|      42|      65|       2
---------------------------------------------------------------------------
   42-   65 (28.05/26.68)	QVkVPEVAISKKQAqTKQQPQQSK
   71-   92 (36.69/23.69)	QL.VRSLQLSQNKS.TFTTPQESK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.73|      23|      24|     633|     655|       3
---------------------------------------------------------------------------
  611-  639 (32.90/12.24)	RNRSASP..VRDGDGRYG...........YRQT.......ARH
  640-  680 (28.33/ 9.58)	RTPPPAR..PRSTAENYGaraelradlfaHRRTgselapgGRV
  681-  714 (29.51/10.27)	RSPPPSRkaPIELFANKG..stapavkelFPDK.......AGH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.06|      23|      24|     372|     394|       4
---------------------------------------------------------------------------
  372-  394 (39.07/27.08)	MMTVEDGELQDGGQEILPHKIHI
  397-  419 (38.99/27.01)	LETLQTQDIENFTHDHFPSESHV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.21|      23|      25|      95|     117|       5
---------------------------------------------------------------------------
   95-  117 (42.89/25.95)	PWHLR....TEQTPSASTTATRPGQTA
  119-  145 (35.32/20.07)	PYIVRevalTPATPQILLRLTTPSLYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.73|      28|      30|     234|     262|       6
---------------------------------------------------------------------------
  234-  262 (44.70/33.19)	QGME.GCVDL..KAGDrLSLDVRREGDRGSDR
  265-  295 (39.03/23.50)	QIVQtGKVLLaqQCSD.LGLRTRARRTWASPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.80|      22|      45|     438|     459|       8
---------------------------------------------------------------------------
  438-  459 (38.40/23.30)	IAAAALKAFAL.TPTDDP.LEPRR
  484-  507 (32.41/18.45)	VGASKYSKFYLnNPELDPeSRPRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.21|      11|     273|     509|     519|       9
---------------------------------------------------------------------------
  509-  519 (22.91/11.44)	GLRGRGRG.NGY
  783-  794 (18.31/ 7.71)	GFQIRGRGsSGF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27568 with Med18 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FYLNNPELDPESRPRRGGLRGRGRGNGYRRGGGYQDDRYDRPRRRRSSTIEPTFDVNLYDDDPASIKARITPTAPSSDRSRRPRNGEDLFANRAPRNHSATSRRSSSDLLPNSRPDGRLRNRSASPVRDGDGRYGFTEDQPYRQTARHRTPPPARPRSTAENYGARAELRADLFAHRRTGSELAPGGRVRSPPPSRKAPIELFANKGSTAPAVKELFPDKAGHRRQEAKDIRAEEVVSAIGRFDMSDERDSYGRNGGSRNSGQRNGGDLMAKNRGRVNQNGRLTEENGGDDGFQIRGRGSSGFSILGASKSAMPPPDLFDRRAREGVRGGRG
2) SALPSALQPDNDTDAMMTVEDGELQDGGQEIL
492
357
823
388










Molecular Recognition Features






MoRF SequenceStartStop




1) APIELFAN
2) ARAELRADLFAHRR
3) FQIRGR
4) KYSKFYL
5) PDLFDRRAREGV
689
656
784
488
807
696
669
789
494
818