<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27560
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MASAPLSFKPWSLQPNNETSLQDVLARVGNERGAFRDISEASLRDEIANGVSTPSSSESSDDEDDNDALSRPSRPKATTRQELFAARAEMLSEVQSAQNEILLALDFVSLLESSHAPQQAGVTVSQALKAVAPLGTLGTDIWHRMPENRAREGQDNLLATKVRMQTLQKSADDLLAAAGRLEDNVRRETIFWDQVLAISERGWSVSRIPRTQGVLGVHFGFNGSAGEFARRDLAALLPGEDGGIALERGVGTKPKGIKVVVKRDGRVVGSSRLPTMPDEEETTLEARIRHARDSLYDEELFHEMVREARTLTSMGVEMRSSTLSFMPASNASLRIELELVLLEDAKQLEDNTLHHSDDLAQATLLAARLLLGQAHREKIKQKTEPPPPMSDRKDKPPILAIIRPILLVFTHHTLCQRLNAYATNIETLLGNADINATIEPANFTFSLPNDLSSTTSESIINAIFLRPLTATASITVPTPSDETEDFRLDLSIETLSAISLGSAFSIRLPSASAAAAVGTPQAFTLSAIEDLFSTADEMLATQMLEVLYPHADPAKAWSLIPAEGKLCRNVGDEEDGAQEEVRLDIDGEVGEMDLVFVASDGRETRKGGWKVDKEDLLRNDKSLWEVWKDVVGVDGGEGEDEQEQEVEV |
Length | 648 |
Position | Head |
Organism | Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Zymoseptoria.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.326 |
Instability index | 43.26 |
Isoelectric point | 4.71 |
Molecular weight | 70838.62 |
Publications | PubMed=21695235
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP27560
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 115.48| 37| 44| 439| 477| 1
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439- 475 (61.27/35.33) EPANFTFSLPNDLSSTTSESIINAIFLRPLTATASIT
482- 518 (54.22/32.53) ETEDFRLDLSIETLSAISLGSAFSIRLPSASAAAAVG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 95.02| 28| 44| 10| 37| 2
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10- 37 (48.47/29.47) PWSLQPNNETSLQDVLARVGNERGAFRD
54- 81 (46.55/28.02) PSSSESSDDEDDNDALSRPSRPKATTRQ
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 37.11| 11| 15| 155| 165| 4
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155- 165 (19.04/12.02) DNLLATKVRMQ
172- 182 (18.07/11.03) DDLLAAAGRLE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 43.37| 13| 15| 280| 292| 5
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280- 292 (21.10/14.00) EETTLEARIRHAR
297- 309 (22.27/15.17) DEELFHEMVREAR
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