<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27554

Description "Serine/threonine protein kinase, CMGC family, CDC2/CDK subfamily"
SequenceMSGTPYAPQRHINDNYDIVGFISSGTYGRVYKAIHKRAVSNPPAKHPDGRNIEAFAIKKFKPDKEGEVQYTGISQSAIREMALCTELSHPALIHLVEIILESKCIFMVFEYAEHDLLQIIHHHSLLPRTPIPASTLRSCMYQIFSGLLYLHRNWVVHRDLKPANIMVTSSGAIKIGDLGLARLFYKPLHALFSGDKVVVTIWYRAPELLLGSRHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKQDSKKAVPFQRNQMGKIGEILGLPKKSEWPLLSAMPEFPNLQTVAMHAPNVNRPLGLTKWYRSTVQNNNYGGGGPPDESALDLLRKLLEYDPLKRLTAEQALKHPYFVGGGAESAGGKASTPSWNCFEGLETKYPARKVSTEAHEIATGGGTMSGQKRSVVNDDLGRPGKKAREI
Length419
PositionKinase
OrganismZymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Zymoseptoria.
Aromaticity0.09
Grand average of hydropathy-0.278
Instability index50.03
Isoelectric point9.25
Molecular weight46544.12
Publications
PubMed=21695235

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27554
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     243.82|      76|      84|     125|     207|       1
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  125-  204 (128.06/105.49)	LLPRTPIPASTLRS..CMyqiFSGLLYLH...RNWVVHRDLKPAnIMVTSSGAIKIGD.LGLARLFYKPL...............HALFSGDKVVVTIWYR
  210-  306 (115.76/75.04)	LGSRHYTPAIDLWAvgCI...FAELLSLRpifKGEEAKQDSKKA.VPFQRNQMGKIGEiLGLPKKSEWPLlsampefpnlqtvamHAPNVNRPLGLTKWYR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.61|      50|     301|      31|      82|       2
---------------------------------------------------------------------------
   31-   82 (79.94/54.46)	YKAIhKRAVSNPPAKHPD..GRNIEAFAIKKFKPDK...EG.EVQYTG..ISQSAiREMA
  334-  391 (70.66/39.89)	YDPL.KRLTAEQALKHPYfvGGGAESAGGKASTPSWncfEGlETKYPArkVSTEA.HEIA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27554 with CDK8 domain of Kingdom Fungi

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