<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27554

Description "Serine/threonine protein kinase, CMGC family, CDC2/CDK subfamily"
SequenceMSGTPYAPQRHINDNYDIVGFISSGTYGRVYKAIHKRAVSNPPAKHPDGRNIEAFAIKKFKPDKEGEVQYTGISQSAIREMALCTELSHPALIHLVEIILESKCIFMVFEYAEHDLLQIIHHHSLLPRTPIPASTLRSCMYQIFSGLLYLHRNWVVHRDLKPANIMVTSSGAIKIGDLGLARLFYKPLHALFSGDKVVVTIWYRAPELLLGSRHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKQDSKKAVPFQRNQMGKIGEILGLPKKSEWPLLSAMPEFPNLQTVAMHAPNVNRPLGLTKWYRSTVQNNNYGGGGPPDESALDLLRKLLEYDPLKRLTAEQALKHPYFVGGGAESAGGKASTPSWNCFEGLETKYPARKVSTEAHEIATGGGTMSGQKRSVVNDDLGRPGKKAREI
Length419
PositionKinase
OrganismZymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Mycosphaerellaceae> Zymoseptoria.
Aromaticity0.09
Grand average of hydropathy-0.278
Instability index50.03
Isoelectric point9.25
Molecular weight46544.12
Publications
PubMed=21695235

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27554
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     243.82|      76|      84|     125|     207|       1
---------------------------------------------------------------------------
  125-  204 (128.06/105.49)	LLPRTPIPASTLRS..CMyqiFSGLLYLH...RNWVVHRDLKPAnIMVTSSGAIKIGD.LGLARLFYKPL...............HALFSGDKVVVTIWYR
  210-  306 (115.76/75.04)	LGSRHYTPAIDLWAvgCI...FAELLSLRpifKGEEAKQDSKKA.VPFQRNQMGKIGEiLGLPKKSEWPLlsampefpnlqtvamHAPNVNRPLGLTKWYR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.61|      50|     301|      31|      82|       2
---------------------------------------------------------------------------
   31-   82 (79.94/54.46)	YKAIhKRAVSNPPAKHPD..GRNIEAFAIKKFKPDK...EG.EVQYTG..ISQSAiREMA
  334-  391 (70.66/39.89)	YDPL.KRLTAEQALKHPYfvGGGAESAGGKASTPSWncfEGlETKYPArkVSTEA.HEIA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27554 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KVSTEAHEIATGGGTMSGQKRSVVNDDLGRPGKKAREI
382
419










Molecular Recognition Features






MoRF SequenceStartStop




1) KRSVVNDDLGRPGKKA
401
416