<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27522

Description Uncharacterized protein
SequenceMREGKKDKEPLPIYESHPPQWLPRTHKSADVGYPGFYPPRPGQDEDILSEANVKNGFVLAASVQSEYSTTTDTIKQDVTKNIFDENAVMDLENLMNEIFSRRVENIPLIPPSTFKIPSRVTANDAKRQAWFADLANPDVPLYKLGKSVPHGAKGHDLLDLLHTNNVAIHRAVWFLRVFGANETAGLRNKPSYNPTQYSVDWAIVVTSYLKKQLADIALPSAPRPGLNIKQTFKGVLSDADTKERWISRFTYCLKLLKTFYSEGLVDNRIFLVWLVQQMSSCNLAQAGFVARLADEYLDGLLGNRALARPFVEACLTKLSEIHTTFAQNHLMDLEGLLKTLLQRICMTLSDAFVSPSVWTAHSSLITEALSSNLAGQPGGDQLQSHKDVLSILLDNLTDIKRRNEAMLFRNLPPRALARMGSVVADIQVLNSISSTTDLESVAFFDDASDAASTFGEKLDILLTWSVTPLQYGEHRPYAAITLLRRWRERNGNRAIRRDVSSPEAFLQDQLFDWLDSSDIAGEPGNLRSVAVLFGKFVKHELFSYANYVTRLIARGEPSLSYTQEPGSRHRDFLRWIPIHELTPSLVNQRKVTLHGARARETPEDLSEREIRREIRAVLPIVFGGVSHPQFDSIAAFRESCPTLLVAPRFEQVRTYKQWFLPNFRNHAQGSVNQENLLKSYCTAVELLDMTKCFGSMLELSLIILEHASSVDLLTAVNETFHRFATIWTSMNVTGTITAALHAAHLVWRTRGIQMRSLLALLVEMDNGRHLDVTSREHVAADIASFTHALNPETDHPNPVPSRLPEILLLAEDPNPEGPSILANSLWYKYRTAFDWAWKVWDNTVASLRLIPNMTNETTNRHSIALRYGHFLLHIDKHLPGGFDDQVLQWFLGTGKNEVSGLCAEAWDVLTVVLLYLCIQGALSTTSILRGLVYPAWQLAANVSSDHEAQSLRRYLEAANRLFDLLLLQEGGSITSTLPVELLDLQRIRTRRQDVFREPHFSLFVSNIPTLVFIEKNMVLSDDFRQLAASLRCSACENDDFRQSCYRNLEIVRASFEHPLQSDAIAEPLCEPLVNALKLILSDLSSGGSNVHSFLSRDMSTVLSPWRLAATAIQMQFALRQLGRALGNELTSNAAGESLDKMTSTLFHHSMTSEEAYFIAEMAKGVDGPVAVKFINNGFQYIIEVFSNIPQPAQSAVLLDRVERAGEVVRVLSHVAEPLREAARFAHLQVDIPTQEMLVTVIYGMFNTVESLLTSAADDSETASQATHTLVFLARLLQFDLGFAGMWTSKFREAASNLCTTLFRLVLLHASGPFFGLVAYPLLLDTLFYLIDELSTQAKSGTLDYFRYYPNLTESDLSHDIPIEYRQQLCTLLPQLPANPVVINLSNAYRDPSGHLVHGSPVLNRPWEWTENLGEPAAPMNSDEEHKEREEQVKNSASLSLELFAARHAGGRIIRSSGVVEEPRTESDIRLFEDNVSSESIYRRDWRESRLEFQRELKASGNVFKGEEGDEVGALHVFATQGRAPSRRTSPASSVKSRGSAHGSLRQSPGQLSYHRASTSTMSESIEVDSAGTSSSIVKISHKRKVSTDDEVEIIEGPLPNTSRMKKAKVKTATTKAKTKKR
Length1621
PositionKinase
OrganismSerpula lacrymans var. lacrymans (strain S7.3) (Dry rot fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Boletales> Coniophorineae> Serpulaceae> Serpula.
Aromaticity0.08
Grand average of hydropathy-0.212
Instability index44.17
Isoelectric point6.18
Molecular weight181463.01
Publications
PubMed=21764756

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27522
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     294.29|      91|     554|     723|     815|       1
---------------------------------------------------------------------------
  723-  815 (153.96/121.22)	FATIWTS..MNVTGTITAALHaaHLVWRTRGIQMRSLLALLVEMDNGRHL.DVTSREHVAADIASFTHALN.PETD..HPNPVPSRLPEILLLAEDP.NP
 1282- 1379 (140.33/103.90)	FAGMWTSkfREAASNLCTTLF..RLVLLHASGPFFGLVAYPLLLDTLFYLiDELSTQAKSGTLDYFRYYPNlTESDlsHDIPIEYRQQLCTLLPQLPaNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.67|      14|     713|     173|     186|       5
---------------------------------------------------------------------------
  173-  186 (28.12/13.79)	WFLRVFGANETAGL
  658-  669 (21.56/ 9.05)	WFLPNF.RNHAQG.
  889-  901 (25.99/12.26)	WFLGT.GKNEVSGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.19|      28|     321|     202|     246|       9
---------------------------------------------------------------------------
   29-   58 (48.43/25.56)	ADVGYPGfyPPRPGQD.....EDILSEANVKNGFV
  214-  246 (45.76/60.80)	ADIALPS..APRPGLNikqtfKGVLSDADTKERWI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.52|      43|     712|     334|     392|      12
---------------------------------------------------------------------------
  344-  387 (71.94/64.52)	ICMTLSDAFVSPSVWTAHSSLITE...ALSSNLaGQPGG..DQLQSHKD
 1380- 1427 (66.57/29.28)	VVINLSNAYRDPSGHLVHGSPVLNrpwEWTENL.GEPAApmNSDEEHKE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27522 with Med12 domain of Kingdom Fungi
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