<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27443

Description Uncharacterized protein
SequenceMLLLALSQIHNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVTQNEPVPRGLPNPPGSANGGAHNCRPDVSPATVPGSKPIHELKNRNDIQKLNSPKTEKLGNRKRKGEHRDGHQGPPSKVSKASHELLQNSSPLPTNGIGGSPENFPSPLDVSLHTGPESSRTEHSENDKHSKIPVNAVKPHTSSPGLVKPSSTSSQLKTTVLQHHEKPEEPVGQHQPKSPRCSFSPSNLRHEPFVRQHPTYAPKGSLPSPSQRSHFLDATQASSPSSRAPSLMQPSTPPVPTKRPEASHQPGVEASQHWQEHTSSESHQRHLGTLQHMSPGCKVSSPPGEPLMPRVGFSPEASKMDSDDNAASGSDSKKKKRYRSRDYTVNLDGQVLEGGVKPVRLKERKITFDPMTGQIKPLTQKDSLQVDIPALAEQHRTEPDKPEQKTNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRREARKTHVLVPNSISTDLPGVSREITNDDLNRIRQLHWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length596
PositionUnknown
OrganismMonodelphis domestica (Gray short-tailed opossum)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Metatheria> Didelphimorphia> Didelphidae> Monodelphis.
Aromaticity0.04
Grand average of hydropathy-0.947
Instability index61.95
Isoelectric point9.19
Molecular weight66182.38
Publications
PubMed=17495919

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27443
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     453.07|     100|     101|     165|     265|       1
---------------------------------------------------------------------------
   61-  108 (44.26/12.34)	.............................................LRSWQ...KLIEPVTQN.....................E......PVprglpnPPGSANGGAHNC.RP.......DVSPATVP.GSK.......
  109-  199 (108.11/42.35)	.....PIHELKNRND.IQKL.......NSP.......KTEK....LGNRK...RKGEHRDGHQgP........PSKV.skaSHEllqnssPL......PTNGIGGSPENFPSP......LDVSLHTGPeSSRTEHSEND
  200-  304 (156.85/60.70)	KHSKIPVNAVKPHTS.SPGL.......VKPSSTSSQLKTTV....LQHHE...KPEEPVGQHQ.PKSPRCSFSPSNL....RHE......PF..vrqhPTYAPKGS...LPSPsqrshfLDATQASSP.SSRAPSLM..
  305-  381 (87.89/31.08)	QPSTPPVPTKRPEAShQPGVeasqhwqEHTSSESHQRHLGT....LQHMSpgcKVSSPPG..E.PLMPRVGFSP......................................................eASKMD.SDDN
  418-  480 (55.97/17.20)	KERKITFD...PMT....GQ.......IKPLTQKDSLQVDIpalaEQHRT...EPDKPEQKTN.LQSP...FEQTNWkelsRNE.......................................................
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27443 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PVRLKERKITFDPMTGQIKPLTQKDSLQVDIPALAEQHRTEPDKPEQKTNLQSPFEQ
2) WQKLIEPVTQNEPVPRGLPNPPGSANGGAHNCRPDVSPATVPGSKPIHELKNRNDIQKLNSPKTEKLGNRKRKGEHRDGHQGPPSKVSKASHELLQNSSPLPTNGIGGSPENFPSPLDVSLHTGPESSRTEHSENDKHSKIPVNAVKPHTSSPGLVKPSSTSSQLKTTVLQHHEKPEEPVGQHQPKSPRCSFSPSNLRHEPFVRQHPTYAPKGSLPSPSQRSHFLDATQASSPSSRAPSLMQPSTPPVPTKRPEASHQPGVEASQHWQEHTSSESHQRHLGTLQHMSPGCKVSSPPGEPLMPRVGFSPEASKMDSDDNAASGSDSKKKKRYRSRDYTVNLDGQVLEGGV
414
64
470
412










Molecular Recognition Features






MoRF SequenceStartStop




NANANA