<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27437

Description Uncharacterized protein
SequenceHIIKYHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKADKQNQQQQNQHQQPTANQQQQQQTAPQQQQQNSTQTNGTTGGGGGGACGTGAGLQQSQDSGLNQVPPNKKPRIGPSGTNSGGPVLPSDYQHSTSRLSYQSNVQGSSQSQNAMGYSTSSQQGSQYHPSHQSHRY
Length396
PositionKinase
OrganismOrnithorhynchus anatinus (Duckbill platypus)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.824
Instability index57.53
Isoelectric point8.82
Molecular weight44722.68
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27437
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.64|      27|      40|     172|     204|       1
---------------------------------------------------------------------------
  172-  204 (37.66/36.10)	PTlqkdfRRTTYANSSLIKYMEKHKVkPDSKVF
  215-  241 (48.98/28.90)	PT.....KRITSEQALQDPYFQEDPL.PTSDVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     136.27|      30|      35|     279|     309|       2
---------------------------------------------------------------------------
  255-  278 (32.57/11.21)	NEDEPEEKADKQNQQQQNQHQQPT......
  280-  309 (53.69/25.43)	NQQQQQQTAPQQQQQNSTQTNGTTGGGGGG
  316-  345 (50.00/26.92)	GLQQSQDSGLNQVPPNKKPRIGPSGTNSGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.44|      15|      35|      46|      60|       3
---------------------------------------------------------------------------
   46-   60 (26.77/16.37)	DLKPANILVMGEGPE
   84-   98 (28.67/17.95)	DLDPVVVTFWYRAPE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27437 with CDK8 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) TKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKADKQNQQQQNQHQQPTANQQQQQQTAPQQQQQNSTQTNGTTGGGGGGACGTGAGLQQSQDSGLNQVPPNKKPRIGPSGTNSGGPVLPSDYQHSTSRLSYQSNVQGSSQSQNAMGYSTSSQQGSQYHPSHQSHRY
216
396

Molecular Recognition Features

MoRF SequenceStartStop
1) AMGYSTSS
2) LNQVPPNKKPRIGPS
3) QYHPSHQSHRY
4) RLSYQSNV
374
325
386
358
381
339
396
365