<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27434

Description Mediator of RNA polymerase II transcription subunit 31
SequenceMMMDGDVASPQADGLGAGVSEVPTLKDAVEGGAQHSLGRAQDAPRVMDGDAAPPQADGLGAGVIQVPALKAAVEGGAQHSLGRAQDAPRVMDGDVAPPQADGLGAGVIPVPALKAALEGGAQHSSGRAQDAALMLMLPPMRIQAKGLPPQVAAGQSCPASGHRPTRRGGRARGGGEGEGLAGVRARPGPPPSHKAPDRKWPLPPPLGEVVGGQAGREPLPAPRAGLAGAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQNNTSGK
Length356
PositionMiddle
OrganismOrnithorhynchus anatinus (Duckbill platypus)
KingdomMetazoa
Lineage
Aromaticity0.06
Grand average of hydropathy-0.454
Instability index40.94
Isoelectric point8.58
Molecular weight38037.88
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27434
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     330.78|      43|      43|      28|      70|       1
---------------------------------------------------------------------------
    3-   46 (83.80/34.77)	MDGDVASP...QADGLGAGVS...EV............PT..LKdAVEGG.AQHSLGRAQ.DAPRV
   47-   90 (86.61/36.16)	MDGDAAPP...QADGLGAGVI...QV............PA..LKaAVEGG.AQHSLGRAQ.DAPRV
   91-  134 (83.64/34.69)	MDGDVAPP...QADGLGAGVI...PV............PA..LKaALEGG.AQHSSGRAQ.DAALM
  135-  183 (44.93/15.58)	L...MLPPmriQAKGLPPQVAagqSC............PAsgHRpTRRGG.RARGGGEGE.GLAGV
  184-  224 (31.80/ 9.11)	RARPGPPP..................shkapdrkwplpPP..LG.EVVGGqA....GREPlPAPRA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.22|      35|      44|     247|     290|       2
---------------------------------------------------------------------------
  247-  288 (51.86/63.09)	LEFVQCLANPNYLnflaQRGYFKdKAFVN.....YL..KYLLYWKEpeY
  292-  333 (57.36/37.19)	LKYPQCLHMLELL....QYEHFR.KELVNaqcakFIdeQQILHWQH..Y
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27434 with Med31 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EGGAQHSLGRAQDAPRVMDGDVAPPQADGLGAGVIP
2) MMMDGDVASPQADGLGAGVSEVPTLKDAVEGGAQHSLGRAQDAPRVMDGDAAPPQADGLGA
3) PALKAALEGGAQHSSGRAQDAALMLMLPPMRIQAKGLPPQVAAGQSCPASGHRPTRRGGRARGGGEGEGLAGVRARPGPPPSHKAPDRKWPLPPPLGEVVGGQAG
74
1
111
109
61
215










Molecular Recognition Features






MoRF SequenceStartStop




NANANA