<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27409

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRELCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGSPATGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHSEQLHKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRYNCDCTDFLLQECGKQGLLSEASVNNLVAKRAADRKHVPQLKSSENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGSGESTKAASVRALLFDISFLMLCHVAQTYGSEVILSESSAGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length989
PositionTail
OrganismEquus caballus (Horse)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Perissodactyla> Equidae> Equus.
Aromaticity0.07
Grand average of hydropathy0.022
Instability index47.51
Isoelectric point6.47
Molecular weight110121.88
Publications
PubMed=19892987

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27409
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.99|      47|     186|     704|     757|       1
---------------------------------------------------------------------------
  704-  757 (73.23/64.52)	KRPIKEVLTDIFakVLEKGWVDSRSIHIfdtllHMGGVYWFCNNLIKELLKETR
  894-  940 (83.76/55.20)	RDPLNRVLANLF..LLISSILGSRTAGP.....HTQFVQWFMEECVDCLEQGSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     175.18|      51|     115|     650|     701|       2
---------------------------------------------------------------------------
  650-  701 (85.32/55.35)	LYSENTLQFYNERVVIMSSILEHMCADVlQQTATQIKFPSTGVDTMPYWNLL
  768-  818 (89.87/54.41)	LYSIFCLDMQQVTLVLLGHILPGLLTDS.SKWHSLMDPPGTALAKLAVWCAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.24|      39|      68|     481|     522|       3
---------------------------------------------------------------------------
  481-  522 (59.86/51.97)	ESTKAASVRALLFDISFLMLChvaQTYGSEVILSESSAGAEV
  550-  588 (66.38/48.42)	DSTKVESLVALLNNSSEMKLV...QMKWHEACLSISAAILEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.67|      35|      68|     368|     406|       4
---------------------------------------------------------------------------
  368-  406 (53.15/50.91)	GKQG.LLSEASVNNLVAKRAADRKhvpqLKSSENANIQPN
  437-  472 (53.52/38.91)	GVLGhMLSGKSLDLLLAAAAATGK....LKSFARKFINLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.22|      22|     115|     292|     317|       8
---------------------------------------------------------------------------
  295-  317 (33.26/28.24)	ESPEGTEELKwTAFTF.LKIPQVL
  326-  348 (34.95/15.50)	GDKDFTEDVN.CAFEFlLKLTPLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27409 with Med24 domain of Kingdom Metazoa
Unable to open file!