<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27404

Description Mediator of RNA polymerase II transcription subunit 1
SequenceMEFSLLPAQRESEVTRLVPVKHLEKSLLEKLRLKYSQKPWNETIKLTRLCLDKPVGNALKCSLYHPVLRCKNMLQEALKAKSLSVILSRIECISKQKGLDSHLGPNEKICYITSEMFYIEVQVKKNGNVSSVKLAHHGETPVVCNELLQFLRAKDFKAFGRSLEGLLLLYNIPGNSEIKAKVYIALRSLEADLSAMFNLYSSKKPNDKEFAILHGQVGYLSPRCGGTPMGIEYYISPCVLLEEKLKPGSLVGGYKAYLSIMGSNNWFLLPNSPLFSGLQQDSNMPSFSVLTEECSMDLPACFCFMFTDPLPLLLPFVQKIQCITGLPVAGIKQAPFHELITHLENSCCTTDEASTDAQFILSIPDCRDHCYAITSVTDNKEALMGILVDKIPFTHPSQVPPTLEVLRHQAAYSTLINSCISSTRKTKVECTDMTHFEISLQKNCRIGISFQNPSGVGLSCVAVDVLSSRQLKCILYKDAVDPSFPCNNEFIVKVLQCCMSIPITMRAILKKSQNTRAVSKMETYSATVHPLTTQGIERDVSMALHHDKQQVNSPDKKVLGHNKHKAVNGNLGHEMAAQSAEHNSDFTIETYRFAAQFNCNIVEEQSTSFAKESSPIMAEGPVPLMAEVPCQVMLGGPSSVILEVSSPVLSEEPSSSMTEHSSSFTGDLSTSITEEFNLNVSGFMVSEKKN
Length690
PositionMiddle
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.099
Instability index48.27
Isoelectric point6.70
Molecular weight76390.52
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27404
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     162.22|      50|      74|     314|     363|       1
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  314-  349 (56.68/34.13)	..........................................LPFV.......QKIQCITGLPVAGIKQA.PF.HELITHLENSCCT
  350-  421 (60.76/37.11)	TDEASTD.AQFILSIpdcrdhcyaitsvtdnkealmgilvdkIPFT.......HPSQVPPTLEVLR.HQA.AY.STLI....NSCIS
  426-  498 (44.78/25.43)	TKVECTDmTHFEISL..........qkncrigisfqnpsgvgLSCVavdvlssRQLKCI..LYKDAVDPSfPCnNEFIVKVL.QCC.
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.29|      27|      72|      53|      81|       2
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   53-   81 (40.57/35.78)	KPVGNALKCSLYH....PVLrCKNMLQeALKAK
  124-  154 (41.72/26.69)	KKNGNVSSVKLAHhgetPVV.CNELLQ.FLRAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.58|      31|     405|     215|     249|       3
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  215-  249 (52.29/37.52)	GQVGYLS..PrCG...GTPMGIEYYISPCVLLEEklkPGS
  620-  655 (48.29/24.52)	GPVPLMAevP.CQvmlGGPSSVILEVSSPVLSEE...PSS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27404 with Med1 domain of Kingdom Metazoa
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