<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27356

Description Mediator of RNA polymerase II transcription subunit 13
SequenceAELTGIKWRRYRYQGPGECGPVISAPAQDDPILLSFIRCLQANLLCVWRREVKPDRKELWIFWWGDEPNLGDVIHHELHMDEEGLWENGLSYECRTLLFKAIHNLLERCLLDKNFVRIGKWFVKPCEKEEKSLSKSENLSCSFTFFLHGESNVCTSVEIAQHQPVYLINQQHLHLAQTSHAPCQVILSPYGLSGTLTGHGYKTSDPTTRKLLEEWRPFYPTVLRVRQDQQEELQYNDDFPAAVEVIVGGVRLVYPSAFVLIAQSDLPLSSSVGGAGHSSTGGQQCTAVTKDPSPCRMPLTPPTSPEQIAPGDGKENPSSINSHSTEDGVSNPKQSSKCGEKSCHRLSSYMAQRVWKECIVNRCQPKLSKMETCQQEGEIQISKAPWDFVDPTHRATCSCSRHKYSKQRSAPSGSRPSSVTQPNMGGIPTSCSSSLPPPASSKHKPTDRQEKAEKLQKKTTTPFHHRALPIQNEQCLTQEMAIQQRQGAEAATSTPPNRQYQSMPSAGELDQLLTSQPSDSPHSPASPMPPTLSPQPPQQEVAIPDPEVQPCNSTLYPNGLEMQPLDDRTMMAAGLGLPLMAELSETSIYCSSLSQSQQTENSWQEYMLPSTGNEDFRPPNIPVEWHESIQETGEDSTALERLLAQPNKRFKVLDENRPILSDNRTYLDQPPMYLEQLGDNLDPYTFEDGEIKYSFTATKKCKMGAERDLSRKLKADEGFEKNASPTEQPASVTDPGKNVMSIFSPASKPDPRQDRGIAASLTQVKDLAPSLNDLDNLFDNSEDEDLAGSPGTRAMKAPSVGSEDRALGKDARTAVAYSATDLQRMFPTPPSLEQHPAFSPIMIYKDGVSSETTATLAMMESPMVNLASMHHLEFKMEVEEGLCSPKPEEIRDFSYVHRVASSQPFVGTSMFAPLKSLPSQCLLSLKIPDACVYRPSWAAPPKMQHLPLPPATSFNRDGYMNVPSVGSLTDPDYLQLNTPQTNTPLAPCSTAPASNSGTGGVLPSPATPRFSVPTPRTPRTPRTPRGGGGASGQGSAKYDSTDLCSPASTPSTTRPLSSVEPASSHPAPEAHSLYVTLLLSDSVLNIFKDRNFDSCCICACNLNIKGADVGIYIPDSSNEDQYRCTCGFSAIVNRRLGYNSGLFIEDEMDIFGRSSDLGQAVERRLNIRVTERLGQEQPPPGLLLLLQRQCTRPFNNCSSTWELSYCQGVSLLDRPSWNYDRVRAESSDAWPECLNALEQGRQYVDNPTGGRVDEALVKSATFHLWPHSNVLDVSMLPSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGSYGSEESPEPLPIPNLLVGYDKDFLTIAPFSLPFWERLLLEPYGGQRDVGYLVLCPENSALLDGAKAFFRDLSAVYEMCRLGEHRPICKVLSDGIMKISQPAGDSEETSCEEMDNQARLQLFAQTCRQHLAPYLSTLQLDSSLLLPPKNQPPTVQTSSSPAVPSCPTGVLFNTTPNGTSTTPLPPPPLSSSTSLPAGNSTVPTGFNNCPSQNTSSIVERPLGNQTTGDPEPSQQSMQQETPENNSATEREKIGIPTEPEPAGALSSCPTVVIYMVDPFTYTVDEDCHPGNYWMLGLIRCFTDMLESLPEPLRSACILQVVPCHSLLQTVNDEVVSYIQHLKSLAFSVYCQCRRPIATQIPIKPLTGFGPAAALNAILRNQEQPSPGQMYSPPFLLSPTKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWLLASCTDLQGELLETCVVNIHVPNRFRRSKVSARKIGLQKLWEWCVEIIQTTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISRQLKETCKMCGISAADSPSILSACLVAMEPQGSFTVMPDAVTMGSVFGRSTALNLQTSQLSTPQDASCTHILVFPTSATIQVSPANYHNEDDFSVSFSDMLDLPFLDDMDNDIGILITGNLHSPPNSSPGSPTGAGPHFQHSRSQVERLLSRETPEELKQQPLALGYYVSTAKAENLPEWFWSSCPHAQNQCPLFLKASLHHHISVSHNDDLVPARTSQRVPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFTVLTQMYNMVMDFL
Length2123
PositionMiddle
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.437
Instability index58.47
Isoelectric point5.47
Molecular weight234328.03
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27356
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.81|      23|      26|     978|    1000|       1
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  978- 1000 (42.11/14.14)	TPQTNTPLAPCSTAPASNSGTGG
 1007- 1029 (36.89/11.51)	TPRFSVPTPRTPRTPRTPRGGGG
 1474- 1495 (32.81/ 9.45)	.PKNQPPTVQTSSSPAVPSCPTG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.09|      25|      26|      36|      60|       2
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   36-   60 (47.78/33.90)	FIRCLQANLLCVWRREVKPDRKELW
   62-   86 (51.31/37.04)	FWWGDEPNLGDVIHHELHMDEEGLW
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.58|      24|      26|    1872|    1895|       3
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 1872- 1895 (44.89/25.17)	AMEPQGSFTVMP.DA.VTMGSVFGRS
 1897- 1922 (34.70/17.77)	ALNLQTSQLSTPqDAsCTHILVFPTS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.23|      14|      26|    1516|    1531|       4
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 1516- 1531 (20.96/17.97)	SSSTSLPAGNSTvpTG
 1541- 1554 (26.27/14.71)	SSIVERPLGNQT..TG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.39|      26|      26|     750|     775|       5
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  750-  775 (43.71/26.22)	DPRQDRGIAASLTQVKDLAPSLNDLD
  779-  804 (44.68/26.97)	DNSEDEDLAGSPGTRAMKAPSVGSED
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.67|      16|      26|    1282|    1303|       6
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 1282- 1303 (22.38/27.03)	VRMLLSLQPFlqdaiqKKRTGR
 1311- 1326 (32.29/20.82)	VQGPLTWQQF......HKMAGR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     190.31|      32|      33|     493|     524|       7
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  294-  317 (34.72/14.19)	.PCRMPLTPPTSPE.......QI...APGDGKENP................
  421-  461 (35.01/14.39)	QPN..MGGIPTSCS......SSL..PPPASSKHKPtdrqekaeklqkktTT
  462-  494 (31.01/11.66)	PF..HHRALPIQNEqcL...TQEMAIQQRQGAEA.............atST
  495-  528 (52.89/26.56)	PPNRQYQSMPSAGE..L...DQLLTSQPSDSPHSP............asPM
  529-  557 (36.69/15.53)	PPTLSPQ.PPQ.QE..VaipDP..EVQPCNSTLYP................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.28|       9|      27|    1766|    1775|       8
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 1766- 1775 (12.45/10.93)	LQgELLETCV
 1796- 1804 (20.83/12.69)	LQ.KLWEWCV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.33|      25|      28|    1091|    1115|       9
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 1091- 1115 (49.22/28.70)	NFDSC.CICACNLNIK...GADVGIYIPD
 1118- 1146 (38.11/20.62)	NEDQYrCTCGFSAIVNrrlGYNSGLFIED
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.96|      29|      33|    2000|    2032|      11
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 2004- 2032 (56.19/42.75)	KQQPL....ALGYYVSTAKAENL.PEWFWSSCPH
 2035- 2068 (44.77/22.88)	NQCPLflkaSLHHHISVSHNDDLvPARTSQRVPH
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     116.39|      30|      32|    1207|    1238|      12
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 1185- 1206 (21.74/ 7.69)	....LLQRQC....TR..PFNNCSSTWelSYC....
 1207- 1237 (51.72/32.98)	QGVSLLDRPSWN.YDR..VRAESSDAW..PEClNAL
 1239- 1271 (42.93/26.02)	QGRQYVDNPTGGrVDEalVKSATFHLW..PHS.NVL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.98|      16|      27|     643|     658|      13
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  641-  656 (27.09/16.75)	RL........LAQPNKRFKVLDEN
  657-  680 (23.88/13.63)	RPilsdnrtyLDQPPMYLEQLGDN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.98|      11|      27|    1346|    1356|      15
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 1346- 1356 (20.74/12.48)	GYDKD..FLTIAP
 1371- 1383 (17.24/ 8.98)	GGQRDvgYLVLCP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.08|      17|      27|     912|     936|      16
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  912-  936 (27.20/28.46)	AP..LKSLPsqcllslkIPDACVY.R......PS
  939-  964 (19.87/ 6.47)	APpkMQHLP........LPPATSFnRdgymnvPS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.66|      18|      30|    1623|    1640|      18
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 1623- 1640 (31.61/20.01)	LIRCFTDMLESLPEPLRS
 1652- 1669 (29.05/17.71)	LLQTVNDEVVSYIQHLKS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.51|      22|     160|     882|     904|      19
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  882-  904 (38.62/25.23)	LCSP..KPEEIRDFSYVhRVASSQP
 1043- 1066 (38.89/20.33)	LCSPasTPSTTRPLSSV.EPASSHP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.12|      28|     311|     375|     420|      23
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  323-  350 (51.25/32.45)	HSTEDGVSNPKQSSKCGEKSCHRLSSYM
  393-  420 (50.87/14.59)	HRATCSCSRHKYSKQRSAPSGSRPSSVT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27356 with Med13 domain of Kingdom Metazoa
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