<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27340

Description transcription elongation factor A protein 1
SequenceMSTSNEEEVLYIAKKLDKMVSKKSADNALDVLKALKQIPINLDTLQKTRIGMSVNNIRKQTANDEVAIAAKQLIKGWKKLVSEPSSASKKSEDNKKKEKPEPIISTNIRKTSTTKMEVSASSHTMDTSSLQSTGNSVRDKCREMLVRGLQTDNTSGHSDQQCAFLAAAIEEAIYSEFKDTGVKYKNRIRSRFSNLKDTRNSILRLNVLNGILKPEQIAKMTAEEMASDEMKKKREEYEQQNIKDHQMSVNEGTKTDMFVCGRCKGRACTYNQLQTRSADEPMTTFVFCTECGNRWKFC
Length298
PositionUnknown
OrganismCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Tunicata> Ascidiacea> Phlebobranchia> Cionidae> Ciona.
Aromaticity0.05
Grand average of hydropathy-0.755
Instability index52.96
Isoelectric point9.24
Molecular weight33662.09
Publications
PubMed=12481130
PubMed=15114417

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27340
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.85|      27|      50|     170|     202|       1
---------------------------------------------------------------------------
  170-  202 (39.72/42.91)	EEAIYSEFKdtgvkyKNRIRSRFSNLKDTRNSI
  223-  249 (46.13/32.81)	EEMASDEMK......KKREEYEQQNIKDHQMSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.47|      29|      65|      21|      53|       2
---------------------------------------------------------------------------
   21-   53 (43.66/37.18)	SKKSADNAldvlKALKQIPI...NLDTLQKTRIGMS
   88-  119 (44.81/28.59)	SKKSEDNK....KKEKPEPIistNIRKTSTTKMEVS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27340 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PSSASKKSEDNKKKEKPEPIISTNIRKTSTTKMEVSASSHTMDTSSLQSTGNSV
84
137










Molecular Recognition Features






MoRF SequenceStartStop




NANANA