<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27334

Description Transcription elongation factor A2
SequenceGGAGAGTTRPKMQRGGAAEPEARPERAAHGTMMGKEEEIVRIAKRLDKMVTKKSTDGAMDLLKELKSMPITLDLLQSTRIGMSVNALRKQSTDDEVISLAKSLIKSWKKLLDASEDKNDEKKRNSSLATSSSKDASDTKDQSSNKKQDPPRTISTPKITTFPPIPITCDAVRNKCREMLTAALQTDNDHVAIGADCEHLSAQIEEYILKEGLPENTDMKYKNRVRSRISNLKDSKNPDLRKNVLCGAITPEQIAVMTSEEMASNELKEIRKAMTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKVG
Length334
PositionUnknown
OrganismMonodelphis domestica (Gray short-tailed opossum)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Metatheria> Didelphimorphia> Didelphidae> Monodelphis.
Aromaticity0.02
Grand average of hydropathy-0.766
Instability index45.96
Isoelectric point9.07
Molecular weight36969.87
Publications
PubMed=17495919

Function

Annotated function 
GO - Cellular Component
centrosome	GO:0005813	IEA:Ensembl
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27334
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.00|      20|      22|     102|     123|       1
---------------------------------------------------------------------------
  102-  123 (30.94/27.89)	SLIKSWKKllDASE..DKNDEKKR
  126-  147 (29.06/19.07)	SLATSSSK..DASDtkDQSSNKKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.21|      17|      27|     238|     254|       2
---------------------------------------------------------------------------
  238-  254 (29.32/21.23)	DLRKNVLCGAITPEQIA
  268-  284 (28.89/20.82)	EIRKAMTKEAIREHQMA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.31|      12|      26|     291|     302|       3
---------------------------------------------------------------------------
  291-  302 (22.42/13.78)	TDLFTCGKCKKK
  319-  330 (22.89/14.20)	TTFVVCNECGNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.66|      25|      26|     164|     188|       4
---------------------------------------------------------------------------
  164-  188 (43.18/30.38)	IPITCDAVRNKCRE.MLTAALQTDND
  192-  217 (37.48/25.47)	IGADCEHLSAQIEEyILKEGLPENTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.40|      21|      25|      25|      47|       5
---------------------------------------------------------------------------
   25-   47 (30.83/28.94)	ERAAHGTM.MGKEEEIVRIAkrLD
   52-   73 (30.57/21.09)	KKSTDGAMdLLKELKSMPIT..LD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27334 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASEDKNDEKKRNSSLATSSSKDASDTKDQSSNKKQDPPRTISTPKIT
2) GGAGAGTTRPKMQRGGAAEPEARPERAAHGTMMGKEEEIVRIAKRLDKMVTKKSTDGAMDLLK
113
1
159
63










Molecular Recognition Features






MoRF SequenceStartStop




1) EARPE
2) EIVRIAKRL
3) GAGAGTTRPKMQRGGAAE
4) IKSWKKLL
21
38
2
104
25
46
19
111