<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27326

Description Mediator of RNA polymerase II transcription subunit 6
SequenceVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFRDQEEQAVVKDEKAKRKEEPSSIFQRQRVDALLLDLRQKFPPRYVQQKLGEKPVPVEQTKKEPEPAPETLKPEEKETPKSAQQTAGPKGPPEKRLRLQ
Length156
PositionHead
OrganismOrnithorhynchus anatinus (Duckbill platypus)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.844
Instability index56.62
Isoelectric point8.89
Molecular weight17909.20
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27326
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.19|      22|      22|      96|     117|       1
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   96-  117 (39.67/19.55)	QKFP...PRYVQQKLGEKPVPVEQT
  118-  142 (32.53/14.96)	KKEPepaPETLKPEEKETPKSAQQT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.75|      12|      22|      58|      69|       2
---------------------------------------------------------------------------
   58-   69 (19.99/15.35)	FRDQEEQAVVKD
   82-   93 (19.75/15.09)	FQRQRVDALLLD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27326 with Med6 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QKLGEKPVPVEQTKKEPEPAPETLKPEEKETPKSAQQTAGPKGPPEKRLRLQ
105
156










Molecular Recognition Features






MoRF SequenceStartStop




1) KDEKAKRKEEPSSIFQRQRVDALLLDLRQKFPPRYVQQKL
2) KEPEPAPETLKPEEKETPKSAQQTAGPKGPPEKRLRLQ
68
119
107
156