<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27305

Description Uncharacterized protein
SequenceMSLLSFYQNRWLLRQRLGPADVYPQEAKQKEDELTSVNVKQGFINQPPFNEEYSSAHLYTIDANKINQSFNQILTQKQVVTTFNDAGAGKRLKPQVYKEQFWLVPVINAKCRVHLQTWFKDLIRGTSLLNLCRRVPVFSKKDDLFRTLSEYEVPMVRATWVIKITSAYHLTQTDAKIKKRAANDPNLEWTQAICRFMREHLVKLNNDNNNQPNSNSSMNLSSGIETVCIMLKYISCLAHHMYSEGLFDRNEFLSWVVDEFECISLYDEIALSYFVPILQNYIEEVTMNQLLARRMSFAAARHLSWLFIEGANSRSQSPALQSGFNMNNTPGTSTPQLTRPTSVQLKQQCPEHLLSIAHTLACVIQCTVITCPGALVWYQPFDAKASGSPLDLLPCAPSDLPLPDIPNNNTFCINYRLLLQEQEADIVRRSRASEMKWSTDKCQESTTGHTINRVLSALEALDKQHFDRRPADSWGDPLDLLYHKIFDQGHGKDGDNQLTKSSEDAVIGLLCEWAISPKRLGEHRAAVVAKLLELRQSHHEQVEYPDTTIETDTSLNTSVGGNNVPYFQNLLFTFLDQQAPELKNPKDGEETQSFKNLVLLFSELIEHDVFSHDIYMNTLISRGEISPGTNESVFSPGECRSDRHFLDAVRSSMENPNKSSANFDASDGSYSNIWGHGQPRHVQYLMHFPISFQEDGMTQEWNQRLMVLYGAGRLKTDVKRAVRKVTRHLTKLVQCKRTMDDGVDTNPTLTPSGKKIKKSPKSSHIELLSRYRVLSYFDQHMITSTVAKSLLTAINNYIAGRSSCLPRLEVVLLLFDLMEEALNVGGLVRTAVAIATRLADLANEIQRRKAETNSLNVEYVWYTTELSLAVVSVLRHYISFLTLNMDLTFNAFEGLLDATKQSCISNPTQCASADRSVLVFLYDLYTSFGYIRSQRSEAFGGYVASVRQALCSTKKPATTNCRYDQTFLQSFIDDPMAQSPLSVAEKYSGLLQDVSRRYSFVCSAVITVCNGHQDFEKVNALAVLCAEMNARCNELSSEWLGVLRALCFSSCTVNFNDVLLIVEAGDAQIRDPLSLFTAVLIARGCLSLEDVIQHVAIPSLLAACKSRTSPDLPNPDTSARLTCHLLLQLFKAPSSNKSSFRLPFSSDRHLLAAAQHSIAVGAVLAVLKGVLKLGDARLSSGKNAFSHESELCVTSFLKPIGNLDDFDDLHMTGGQSGPSSSMDGASLSEFAKHAVRVICSQQWVREKCLKDPVMDLLMDQVLTREQRQNLIQLICYPENLLQKLSGLSNEPRKYVVSVLSGMTRWTFRQCLLELQVMLRQSPQEKSLPEHIAKATIEVFQQQQQQQNLDSTKERKSSLTGPELDRCNVWLVAPLVSKLPSQVQGRVLQEASAILEAPQNLSSTSTRSGAGARSERDNRQGGSSLLNHQPFLTLILTCLKGQDEQRDSLLESLQSQIVMLHSEWQDARSHRGSCKDLNNSQNCVHDALQLRLSLVGGMFDTVMSNSQWTSDVVVLLMQLIISGMVDVQTNSELFDIVYDMIAVLLHHTLGGDCANKGEGSKREYINIVKKMKKEMGDKQTESIRRLRQLLPITRPEVYVVCCEPSGAHMDIKGNKIPVPVDGNQGLQVTSKQKLNMWDVIEGLKHSSPLCLAWFGARTIERKPMFYEEQHNLMLHHQHSRKRWKIFYFLSPPQLPPEEEEEAELIPVPTKIPDHKGSVLKNPFGASSASTEGMKQPPPKKKKKSRV
Length1745
PositionKinase
OrganismCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Tunicata> Ascidiacea> Phlebobranchia> Cionidae> Ciona.
Aromaticity0.07
Grand average of hydropathy-0.296
Instability index50.48
Isoelectric point7.25
Molecular weight196223.90
Publications
PubMed=12481130
PubMed=15114417

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coactivator activity	GO:0003713	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27305
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     304.94|     142|     218|    1107|    1256|       1
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 1107- 1164 (54.34/30.55)	..........................................................................................................................................................RTSPDLPN.PDTSARLTCHLLLQL.....FKAPSSNKSSFRLPfSSDR...HLLA...AAQHSIAVGAVL
 1165- 1256 (99.91/80.27)	AVLKGVLKLGDARLSSGKNAFSHESELCVTSFLKpigNLDDFDDLHMTgGQSGPSSSMDgaSLSEFAKHAVrVICSQQWVREKCLKDPVMDL....................................................................................................................................
 1319- 1387 (33.25/11.87)	............................................................................................lmdqvltreqrqnliqlicypenllqklsglsneprkyvvsvlsgmtrwtfrqcllelqvmlRQSPQEKSlPEHIAKATIEVFQQQqqqqnLDSTKERKSSLTGP.ELDRcnvWLVAplvSKLPSQVQGRVL
 1392- 1476 (117.45/69.85)	AILEAPQNLSSTSTRSGAGARSERDNRQGGSSLL...NHQPFLTLILT.CLKGQDEQRD..SLLESLQSQI.VMLHSEWQDARSHRGSCKDL....................................................................................................................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.59|      30|      87|     358|     393|       2
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  358-  393 (45.68/42.97)	HTLAcviqcTVITCPGALVwYQPFD...AKASGSPLDLL
  449-  481 (50.90/28.61)	HTIN.....RVLSALEALD.KQHFDrrpADSWGDPLDLL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     191.22|      64|     214|      61|     136|       3
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   61-  136 (90.72/97.29)	IDANKINQ.SFNQILTQKQvvtTFNDA.........GAGKRLKPQVYKEQFwlvpviNAKCRVHLQTwfKDLIRGTSlLNLCRRVP
  277-  350 (100.51/69.39)	ILQNYIEEvTMNQLLARRM...SFAAArhlswlfieGANSRSQSPALQSGF......NMNNTPGTST..PQLTRPTS.VQLKQQCP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     303.50|      71|      87|     643|     713|       4
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  574-  638 (88.31/58.37)	..F..LDQQAPELKNPKdgEETQSFKNLVLLFSELIEHDVFSHDIY.MNTLI..SRGE..ISPGTNES...V...FSPGE
  643-  713 (125.09/86.23)	RHF..LDAVRSSMENPN..KSSANFDASDGSYSNIWGHGQPRHVQYLMHFPI..SFQEDGMTQEWNQRLMVL...YGAGR
  727-  801 (90.10/59.73)	RHLtkLVQCKRTMDDGV..DTNPTLTPSG...KKIKKSPKSSHIELLSRYRVlsYFDQHMITSTVAKSLLTAinnYIAGR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     146.79|      45|     246|     802|     846|       6
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  802-  846 (72.10/55.68)	SSCLPRLEVVLLLFDLMEEALNVGGLVRTAVAIATRLADLANEIQ
 1049- 1093 (74.69/58.00)	SSCTVNFNDVLLIVEAGDAQIRDPLSLFTAVLIARGCLSLEDVIQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.40|      25|     294|     980|    1011|       8
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  980- 1011 (34.15/42.16)	PLSVAEKYSGlLQDVSRRYsfvcsaVITVCNG
 1277- 1301 (43.25/29.12)	PENLLQKLSG.LSNEPRKY......VVSVLSG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27305 with Med12 domain of Kingdom Metazoa
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