<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27304

Description Mediator of RNA polymerase II transcription subunit 28 (Fragment)
SequenceAASFFSAMFSAQQPGPPPPNQPGAPAGLMSTPPGAKNPSSTLVDDLESSFEACFASLVSQDYVNGTDQEEIRTGVEQCIQKFLDVARQTECFFLQKRLQLSVQKPEQVIKEDVSELRNELQRKEALIQKHLTKLRSWQQVLEEINGQHKKTSEMPQGPLAYLEQASANIPAPMKPT
Length176
PositionHead
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Amphibia> Batrachia> Anura> Pipoidea> Pipidae> Xenopodinae> Xenopus> Silurana.
Aromaticity0.06
Grand average of hydropathy-0.552
Instability index65.31
Isoelectric point5.27
Molecular weight19482.83
Publications
PubMed=20431018

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
plasma membrane	GO:0005886	IBA:GO_Central

GO - Biological Function
amino acid transmembrane transporter activity	GO:0015171	IBA:GO_Central
arginine transmembrane transporter activity	GO:0015181	IBA:GO_Central
L-lysine transmembrane transporter activity	GO:0015189	IBA:GO_Central
L-ornithine transmembrane transporter activity	GO:0000064	IBA:GO_Central

GO - Biological Process
amino acid transport	GO:0006865	IBA:GO_Central
L-arginine import across plasma membrane	GO:0097638	IBA:GO_Central
L-ornithine transmembrane transport	GO:1903352	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27304
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.83|      18|      30|      93|     111|       1
---------------------------------------------------------------------------
   93-  111 (25.23/21.70)	FLQKRLQlSVQKPEQVIKE
  126-  143 (30.60/21.21)	LIQKHLT.KLRSWQQVLEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27304 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MFSAQQPGPPPPNQPGAPAGLMSTPPGAKNPSSTL
2) NGQHKKTSEMPQGPLAYLEQASANIPAPMKPT
8
145
42
176










Molecular Recognition Features






MoRF SequenceStartStop




NANANA