<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27298

Description cAMP regulated phosphoprotein 21
SequenceMSEQGDLNQGIAEEGGTEQETGTPENGVVKSESLDEEEKLELQRRLEAQNQERRKSKSGAGKGKLTRSLAVCEESSARPGGESLQDQESIHLQLSSFSSLQEEDKSRKDESEREKEKDKNKDKTSEKPKIRMLSKDCSQEYTDSTGIDLHEFLINTLKNNSRDRMILLKMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTGKSVIINKTSSTRIPEQRFCEHLKDEKGEESQKRFILKRDNSSIDKEDNQQNRMHPFRDDRRSKSIEEREEEYQRVRERIFAHDSVCSQESLFVENSRLLEDSNICNETYKKRQLFRGNRDGSGRTSGSRQSSSENELKWSDHQRAWSSTDSDSSNRNLKPAMTKTASFGGITVLTRGDSTSSTRSTGKLSKAGSESSSSAGSSGSLSRTHPPLQSTPLVSGVAAGSPGCVPYPENGIGGQVAPSSTSYILLPLEAATGIPPGSILLNPHTGQPFVNPDGTPAIYNPPTSQQPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMSGPLVTQRDDVATQFGQMTLSRQSSGETEPPSGPVYPSSLMPQPAQQPSYVIASTGQQLPTGGFSGSGPPISQQVLQPPASPQGFVQQAPPAQMPVYYYPSGQYPTSTTQQYRPMASVQYNAQRSQQMPQAAQQAGYQPVLSGQQGFQGLIGVQQPPQSQTVMNNQGTPMQSVMVSYPTMSSYQVPMTQGSQGLPQQSYQQPIMLPNQAGQGSLPATGMPVYCNVTPPTPQNNLRLIGPHCPSSTVPVVSPSCRTNCASMSNAGWQVKF
Length810
PositionKinase
OrganismCallithrix jacchus (White-tufted-ear marmoset)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Cebidae> Callitrichinae> Callithrix> Callithrix.
Aromaticity0.05
Grand average of hydropathy-0.893
Instability index71.05
Isoelectric point6.51
Molecular weight88926.48
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
nucleic acid binding	GO:0003676	IEA:UniProtKB-UniRule

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27298
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     466.00|      60|      60|     668|     727|       1
---------------------------------------------------------------------------
  409-  473 (59.72/15.21)	GSES..SSSA....GSSGSLS..RTHPPlQSTPLVSGvaAGSPG...CVPYPENGiGGQVaP.sstsyiLLP......LEA.AT
  499-  556 (73.58/20.21)	IYNPPTSQQP....LRSAMVGqsQQQPP.QQQP..SP..Q..PQQQVQPPQPQMS.G..............PlvtqrdDVATQF
  557-  589 (58.03/14.60)	G.QMTLSRQS....S.....G..ETEPP..SGP...............V.YPS........S.......LMP......QPAQQP
  590-  637 (46.60/10.47)	SYVIASTGQQlptgGFSG......SGPP.ISQQVLQ...............PPAS......P..qgfvqQAP......PAQMPV
  638-  676 (62.19/16.10)	YYYP.....S....G..............QYPTSTTQ..QYRPMAS..VQYNAQR.SQQ...........MP......QAAQQA
  677-  741 (99.76/29.66)	GYQPVLSGQQ....GFQGLIG..VQQPP.QSQTVMNN..QGTPMQSVMVSYPTMS.SYQV.P.mtqgsqGLP......QQSYQ.
  742-  804 (66.12/17.52)	..QPIMLPNQ....AGQGSL......PA.TGMPVYCNvtPPTPQNNLRLIGPHCP.SSTV.PvvspscrTNC......ASMSNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.09|      50|      63|      33|      86|       2
---------------------------------------------------------------------------
   33-   86 (74.78/51.07)	SLDEEEKlelQRRLEAQ.NQERRKSKSGAG.KGKLtRSLAV.CEESSARPGGESLQD
   99-  151 (69.31/37.49)	SLQEEDK...SRKDESErEKEKDKNKDKTSeKPKI.RMLSKdCSQEYTDSTGIDLHE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.35|      15|      18|     340|     354|       3
---------------------------------------------------------------------------
  340-  354 (24.86/13.77)	RTSGSRQS.SSENELK
  360-  375 (20.84/10.21)	RAWSSTDSdSSNRNLK
  390-  404 (22.65/11.82)	LTRGDSTS.STRSTGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      64.09|      21|      21|     242|     262|       5
---------------------------------------------------------------------------
  242-  256 (18.04/ 7.05)	.......K...............GEESQKR..FILKRDN
  257-  275 (25.91/13.27)	SSIDKEdN...............QQNRMHP..F...RDD
  300-  337 (20.15/ 8.72)	SVCSQE.SlfvensrlledsnicNETYKKRqlFRGNRDG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27298 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GIPPGSILLNPHTGQPFVNPDGTPAIYNPPTSQQPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMSGPLVTQRDDVATQFGQMTLSRQSSGETEPPSGPVYPSSLMPQPAQQPSYVIASTGQQLPTGGFSGSGPPISQQVLQPPASPQGFVQQAPPA
2) KKRQLFRGNRDGSGRTSGSRQSSSENELKWSDHQRAWSSTDSDSSNRNLKPAMTKTASFGGITVLTRGDSTSSTRSTGKLSKAGSESSSSAGSSGSLSRTHPPLQSTPLVSGVAAGSPGCVPYPENGIGGQVAPSSTSYILLPL
3) MSEQGDLNQGIAEEGGTEQETGTPENGVVKSESLDEEEKLELQRRLEAQNQERRKSKSGAGKGKLTRSLAVCEESSARPGGESLQDQESIHLQLSSFSSLQEEDKSRKDESEREKEKDKNKDKTSEKPKIRMLSKDC
4) RFILKRDNSSIDKEDNQQNRMHPFRDDRRSKSIEEREEEYQ
5) TTQQYRPMASVQYNAQRSQQMPQAAQQAGYQP
474
326
1
249
649
633
469
137
289
680










Molecular Recognition Features






MoRF SequenceStartStop




1) ERRKS
2) LDEEEKLELQRRLEA
3) MPVYYYPS
52
34
635
56
48
642