<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27283

Description Mediator of RNA polymerase II transcription subunit 13
SequenceVRMSSCFVPNGASLEDCHSNLFCLADLTGIKWKRYIWQGPTSAPILFPVTEEDPILSSFSRCLKADVLSVWRRDERPGRRELWIFWWGEDPNFADLIHHDLADEEDGIWDNGLSYECRTLLFKAIHNLLERCLMNRNFVRIGKWFVKPYEKDEKPVNKSEHLSCSFAFFLHGDSNVCTSVEINQHQPVYLLSEEHLTLAQQSNSPFQVILSPFGLNGTLTGQSFKMSDSSTKKLIGEWKQFYPISSSVKECSEEKQEDMDWEDDSLAAVEVLVGKVRTILGSRFSHDSTQTAQTAGSCSSQNLKESNHLSFSIIHRASYKQNEIVDAQSAQKWVKFPAVSDCFSSDTTSHHGGKIPRKLANQVVDRVWQECNMNRAQNKRKYSSNGVVCEDESPEKTASWDFVESTQRTTCVCSRHKNLKQRNLNQPGQPVTASTQQQVTQKHKTNDKQEKGDKPQKRPLTPFHHRASISDDVNIEADSASQRLGIRSQDTRGRFSNIRTNDVAKTPQMHNNEMASSPPPPPLSPHPCEVMDDGGETMKNPSTPHSQHFYQMPTPDPLIPVKSIDERIDGLPQTFASAFPEVLEPTMYVGNAVRLEAGETDNSWKYYKVPKKKEAEFNPPQLPNDKLSQLLYLTAQFYFVNRLMVQGKKPLKISEELLHKYQSKNQYIPTAVLDTDQESDPYTFVDDDVEFIFSDTKKERQITDRDVGKKHKQDLHFYLKENITQGHLSVTVLPQEGEDAMSLFSPSVKPEIYNTSGSGIDSGSPLFNIFILQPGSKRALNPDEKANSKESKPGNLDPLSCISKCCATHTRREPLVQPAMLGGTHAPSTADLHKMYPTPPSLEQHFMGFSPMNMNSKDYGNMDTTPGGSLTDGSNFCIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPETCQVLVGCSMFAPLRTLPSQCLPGIKLPEDCIYRPSWTVGKLELIPPVPSMPFIKDGKMNIPSVGSAMDQDYVQTYTPQTHTPFGMSNSAPPSNGGAGILPSPATPRFSAPTPRTPRTPRTPRGGGGPASVQGSVKYDNSDLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMNIKGADVGVYIPDPTQEVQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRHTDSGKEVEKRFEALRAAGGDHGVLRDPEKMPDELILLLHDQCTNLFSPFGTLDQEPITKTSTVSYSARVEEQDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSTCLHRWSKRNAVDASMQCSQDILRMLLSLQPVLQDAVQKKRTVRSWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLVGYDYDFLVLSPFALPYWERLMLEPFGSQRDIAYVVVCPENEALLNGAKSFFRDLTAMYESCRLGQHRAISKQLTDGIMKVGSTAAKKLSEKPVAEWFSQAINGNSEAYSKLRLYAQVCRYELGPYLASQPLDSSLLCQPNLTSSAIQPAAASTPGNPSTPSSLNSSAANSSSTVTPNTLPQAAATGSAATSNVAGGLTANKPTSFPPYGNINSTPNSIPAQVNSVQSNQGGPQTQQQTLQQNSGMSSEQSAAAAAAAAEVTERSTMDRDKVGVPTDGESHAVTYPPAIVVYIVDPFTYESKDEDSNSSSVWMLGLLRCFLEMLHILPPHLRNTVSVQIVPCQYFLQPVRQEDRQIYTQHLKSLAFSVFTQCRRPLPASTNVKTLTGFGPGLAIENALKSPERPDCIRLYTPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWLLASCTDLYGELLETCIINIDVPNRARRKKGSARRCGLQKLWEWCQGLVQMSSVPWRVVIGRLGRIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLTIQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENIDLAFNTNNAKNVMFTAVCFDTGDDLDPDIINNLPTSPTGSQGHSPGSHYPHGGDAGKVFTFLCGQGTDRLLSTESHDEVTNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQNQCPLFLKASLHLHVPSVQSDELLHSKHSHPLDSNQTSDVLRFVLEQYNALSWLTCDPATQDRRSCLPVHFVVLNQLYNFIMNML
Length2175
PositionMiddle
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.426
Instability index51.32
Isoelectric point6.03
Molecular weight240925.45
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27283
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     305.20|      92|     112|     798|     909|       1
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  805-  902 (157.68/104.46)	CCATHTrrePL.VQPAM.LGGTHAP......STADLHKMYPTPPSLEQHFMGFSPMNMNSkdYGN.MDTTPGGSLTDGSNFCIGAQFKIEVDEGFCS..PKPSEIKdFS
  915- 1017 (147.52/72.11)	GCSMFA...PLrTLPSQcLPGIKLPedciyrPSWTVGKLELIPPVPSMPFIKDGKMNIPS..VGSaMDQDYVQTYTPQTHTPFGMSNSAPPSNGGAGilPSPATPR.FS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     370.11|     114|     147|    1170|    1297|       2
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 1170- 1297 (181.78/149.03)	KRFEALrAAGGDHGVLRDPEKMPDELILLLHDQCTNLFSPFG.....TLDQEPITKTSTVSYSArveeqdCCNDCYLALEHGRQFMDNMSggkvdeALVKSTCL..HRWSKRNAVDASMQCSQDILRMlLSLQPV
 1320- 1440 (188.33/121.36)	QQFHKM.AGRGSYGTDESPEPLPIPTFLVGYDYDFLVLSPFAlpyweRLMLEPFGSQRDIAYVV......VCPENEALLNGAKSFFRDLT......AMYESCRLgqHRAISKQLTDGIMKVGSTAAKK.LSEKPV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     464.20|      93|     111|     483|     575|       3
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  375-  463 (96.75/46.09)	..........R.AQNKRKYSS.NgVVCED..E..SPE....KTASWDFVESTQRTTCVCSRHKNLKQRNlnqPGQPVTA..STQQQV.TQKH....KTNDKQEKGdKPQkrpltPF
  483-  575 (162.22/82.53)	R......LGIR.SQDTRGRFS.N.IRTNDVAK..TPQMHNNEMASSPPPPPLSPHPCEVMDDGGETMKN...PSTPHSQ..HFYQMP.TPDPLIPVKSIDERIDG.LPQ.....TF
  594-  684 (118.70/58.31)	R......LEAG.ETDNSWKYY.K.VPKKKEAEfnPPQLPNDKLSQLLYLTAQFYFVNRLMVQG....KK...PLKISEEllHKYQ...SKNQYIPTAVLDTDQES.DPY.....TF
  700-  785 (86.53/40.40)	RqitdrdVGKKhKQDLHFYLKeN.ITQGHLSV..TVLPQEGEDAMSLFSPSVKP...EIYNTSGSGI.D...SGSPLFN..IFILQPgSKRALNP....DEK..............
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.79|      16|      16|    1476|    1491|       4
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 1476- 1491 (29.16/14.52)	QPLDSSLLCQPNLTSS
 1494- 1509 (29.63/14.89)	QPAAASTPGNPSTPSS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.33|      18|     149|     315|     332|       5
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  315-  332 (31.07/23.02)	HRASYKQNEIVDAQSAQK
  465-  482 (30.26/22.21)	HRASISDDVNIEADSASQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.41|      13|      16|    1036|    1048|       8
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 1036- 1048 (23.25/12.62)	PASVQGSVKYDNS
 1053- 1065 (25.16/14.36)	PASTPSTCRPLNS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     295.94|      91|    1643|     191|     289|       9
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  191-  289 (143.99/105.86)	LSEEHLTLAQQSNSPFQVILSPFGL..NGTLTGQSFKMSDSSTKKLIGEWKQFypisssVKECSEEKQEDMDWEDDSLAAVE......VLVGKVRTilGSRFSHDST
 1839- 1937 (151.95/93.72)	LWEWCQGLVQMSSVPWRVVIGRLGRigHGELKDWSCLLSRRNLQSLSKRLKDM......CRMCGISAADSPSILSACLVAMEpqgsfvIMPDSVST..GSVFGRSTT
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.22|      56|    1636|      46|     105|      10
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   46-  105 (95.82/61.83)	LFPVTEEDPILssFSRCLKADVLSVWRRDERPGRRELWI.FWWGEDPNFAdlIHHDLADEE
 1692- 1748 (93.40/50.25)	LQPVRQEDRQI..YTQHLKSLAFSVFTQCRRPLPASTNVkTLTGFGPGLA..IENALKSPE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27283 with Med13 domain of Kingdom Metazoa
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