<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27256

Description Uncharacterized protein
SequenceMAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFSGDEHGSAKNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHNWFSDLAGNKPLTNLAKKELLTLAKSGVVQVPILSKKEDVFAYLAKYSVPLLRAAWLIKMTCAYYSAISEAKIKKRQTTDPNMEWTQISTRYLREQLAKIADFYHLASAPGNGSMAMPQEVEQALKQWEYNEKLAFYMFQEGMLERHEYLTWILDVLEKIRPVDDDLLKLLLPLMLQYSEEFVQSAYLSRRLAYFCARRLSLLLNDSPNLLAAHSPHMMIGPSNPSLSASSPAAPGPVMSPVQMAGSDFLSCPQHRPLVYGLSCMLQTVTLCCPSALVWNYSTNENKSVNPGSPLDLLQVAPSSLPMPGGNSAFNQQVRAKIYEVEQQIKRRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRSDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESLSSASLAGSSLPVFQNVLLRFLDTQAPSLSDPNSEYEKIEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSISATTRPRSPPGENLDEHYSKDNDVKLEEHSIMEHMGIDSGTANIFDDVDKSDFKTDFGSEFPIFSPMPGESCENANSSLDRRISVNSEKMVKREKQRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTECGVDDEGQKARKSKQETFPTLETVFTKLQLLSYFDQHQVTSQISSNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHACLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYSNVQPSNSNLLWDPEFMLDFIENPSAHNVNYSMLGKILSDNAANRYSFVCNALMNVCMGHQDAERINDIANLCAELTACCTVLSSEWLGVLKALCCSSNHVWGFNDLLCSVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDPDAEPGARMTCRLLLHLFRTPQVCLLPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAILMLGDAEIGSNSNANALKSEDFTMRGLLDDMNDDDIWNASQSMKPCGKAVSIETASLSEYARYVLRTICQQEWVGEHCLKEPERLCTDKDLILDPVLSHKQAQKLLQLICYPHGVKECTEGDDLQRQHIKRILQNLDQWTLRQSWLELQLMIKQCMKEPGSGSMTEMNCLLDNIAKTTIEVFQQSADLNNNSSNSGIGLFHPNAIGNGDTSNTRQNGKKTFLSSSERRGVWLVAPLIAKLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQDDVKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMQTNNELFTTVLDMLGVLINGTLASDLSSSSQGGAEENKRAYMNLVKKLNKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGHKNPAPLSWAWFGTVRVDRKVIKYEEQHHLLLYHTHPTPKPRSYYLEPLPLPPEEEEEEPTTPVSQEPERKSAELSDQGKTAAADEEKKTKGRKRKTKSNSRVDEYPQNNIYRVPPNYSPISSQMMHHPQSALWGYNIMGQPQQPGFFLQNQSLAPGGSRLDPTGSFVPTNTKQALSNMLQRRSGTMMQPPSIHAITSQQQLIQMKLMQQQQQQQQQQQQRLLRQQAQTRPFQQDFCNSAVPLQDGFDNIMGQPLDQAAIFAPQVRPSSQLPQYSGLQQAQAMPHGYTMYSTQMPLQPQQQAGGVVLSPGYNPRTYPATHSNPALMERLRQMQQQPPSGYIQQQAAAAAYLQPMPGSQRLTHQPLQQSPLVGGGLDAVLSTTPHPNLNSVPLPQDQMRQRQQQIRQQRLLQLQQQQPQQQQQQPQQQQQQPQTQQQQQQQQQQQQPQGQQALGLQAMQAQQPLFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQGVTPYGHPSHF
Length2235
PositionKinase
OrganismMonodelphis domestica (Gray short-tailed opossum)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Metatheria> Didelphimorphia> Didelphidae> Monodelphis.
Aromaticity0.07
Grand average of hydropathy-0.461
Instability index59.00
Isoelectric point6.54
Molecular weight250776.25
Publications
PubMed=17495919

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro
transcription coactivator activity	GO:0003713	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27256
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     193.95|      22|     109|    1863|    1884|       1
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 1848- 1868 (30.33/ 9.02)	.PISSQMMHHPQSALWGYNIMG
 1869- 1886 (32.15/ 9.98)	QPQQPGFFLQNQSLAPG....G
 1938- 1957 (31.76/ 9.78)	QQQQQQ..QQQQQRLLRQQAQT
 2119- 2139 (24.76/ 6.07)	.PLPQDQMRQRQQQIRQQRLLQ
 2141- 2159 (35.94/11.98)	QQQQPQ...QQQQQPQQQQQQP
 2160- 2181 (39.01/13.61)	QTQQQQQQQQQQQQPQGQQALG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.81|      18|      27|     909|     927|       2
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  909-  927 (26.12/18.74)	AELLLKSSSLAGSYtTGLC
  939-  956 (33.69/19.95)	ACLILNPDQTAQVF.EGLC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     249.16|      41|     150|    1889|    1929|       3
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 1889- 1929 (74.11/42.16)	LDPTGSFVPTNTKQALS.N.MLQRRSGTM.MQ.PP....SIHAITSQQ.....Q
 1962- 1998 (46.14/22.91)	QDFCNSAVPL..QDGFD.N.IM....G....Q.PL....DQAAIFAPQvrpssQ
 1999- 2029 (48.23/24.34)	L.P..QYSGLQQAQAMP.H.GYTMYSTQMpLQ.P............QQ.....Q
 2035- 2072 (56.82/30.26)	LSP.G.YNPRTYPATHS.NpALMERLRQM.QQqPP....S.GYI..QQ.....Q
 2079- 2108 (23.85/ 7.56)	LQP....MPGS..QRLThQ.PLQ........Q.SPlvggGLDAVLS........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.69|      10|      35|    1307|    1320|       4
---------------------------------------------------------------------------
 1307- 1320 (15.97/17.16)	HCLKEperlCTDKD
 1343- 1352 (20.72/10.05)	HGVKE....CTEGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     454.90|     153|     286|     420|     596|       5
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  420-  596 (231.88/210.83)	PMPG.....GNSAFNQQVRAkiyEVEQQIKR.RGRAVEVRWSFDkcqestagvtisrvlhTLEVLD..RHCFDRSDSSNSMETLYHKIFWANQNKDNQEVAP.............NDEAvvTLLC...EWAVSCKRSGKHRAMAVAKLLEKRQ..AEIEAERCG...ESEVLDEKESLSSASlaGSSLPVFQNVLLRFlDTQAPSL
  707-  888 (223.02/152.29)	PMPGescenANSSLDRRISV...NSEKMVKReKQRELIFPSNYD................LLRHLQyaTHFPIPLDESSSHECNQRTILLYGVGKERDEARHqlkkitkdilkilNKKS..TTECgvdDEGQKARKSKQETFPTLETVFTKLQllSYFDQHQVTsqiSSNVLEQITSFASGT..SYHLPLAHHIQLIF.DLMEPAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.89|      19|     148|    1492|    1510|       6
---------------------------------------------------------------------------
 1492- 1510 (31.61/18.63)	LGSSSKKERDRQKQKSMSL
 1633- 1651 (32.27/19.18)	LSSSSQGGAEENKRAYMNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.54|      23|     148|    1231|    1261|       7
---------------------------------------------------------------------------
 1231- 1261 (34.24/34.94)	LMLGD..AEIGSNSNANalksedftMRGLLDDM
 1380- 1404 (38.30/21.84)	LMIKQcmKEPGSGSMTE........MNCLLDNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.32|      12|      27|    1170|    1183|       8
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 1170- 1183 (20.23/19.17)	PGARMTCRllLHLF
 1200- 1211 (24.10/15.25)	PGIRSSCD..RHLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.25|      15|     192|     958|     972|      12
---------------------------------------------------------------------------
  958-  972 (29.13/15.96)	VVKHVVNPS....ECSSPE
 1149- 1167 (24.12/11.94)	VVQHVALPSllaaACGDPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.88|      48|    1357|      52|     105|      14
---------------------------------------------------------------------------
   52-  105 (72.67/58.95)	SGDEHGSAKNivinpSKIGAYFSSILAEKLKLNTFQDtGKKK.PQVNAKDNYWLV
 1415- 1463 (79.21/48.40)	SADLNNNSSN.....SGIGLFHPNAIGNGDTSNTRQN.GKKTfLSSSERRGVWLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.52|      22|     700|     385|     419|      15
---------------------------------------------------------------------------
  385-  419 (31.89/45.31)	LCCPSALVWNYstnenksvNpgsplDLL.QVAPSSL
 1103- 1125 (40.63/23.21)	LCCSSNHVWGF........N.....DLLcSVDVSDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.52|      13|      34|    1725|    1737|      16
---------------------------------------------------------------------------
 1725- 1737 (26.43/14.32)	LFEGHKNPAPLSW
 1760- 1772 (27.09/14.88)	LYHTHPTPKPRSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.39|      11|      27|    2186|    2196|      17
---------------------------------------------------------------------------
 2186- 2196 (22.26/10.28)	QAQQPLFPRQG
 2203- 2213 (17.14/ 6.14)	QQQTAALVRQL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27256 with Med12 domain of Kingdom Metazoa
Unable to open file!