<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27241

Description Mediator complex subunit 23
SequenceMADSDIFFFQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLCNKTLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRISLPGISCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSQLHSLASVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWALHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLDRIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPMQIQPSYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYELHLRERTSLKRKLVHAIIGSLKDNRPQGWCLSDTYLKYAMNPREESPWIPDDTYYCRLIGRLITPMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALTVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLLITALPEPYWIVLHDRIVSVLSSSSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLAEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMEPAAVPPQAINSGSPAPQPSQVPVNVALPVTQ
Length1327
PositionTail
OrganismOrnithorhynchus anatinus (Duckbill platypus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Monotremata> Ornithorhynchidae> Ornithorhynchus.
Aromaticity0.10
Grand average of hydropathy0.009
Instability index45.09
Isoelectric point7.57
Molecular weight151849.07
Publications
PubMed=18464734

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27241
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.57|      16|      17|     952|     967|       1
---------------------------------------------------------------------------
  952-  967 (31.59/22.87)	YKFHDRPVTYLYNTL.H
  969-  985 (23.98/15.39)	YELHLRERTSLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.80|      11|     127|     541|     561|       2
---------------------------------------------------------------------------
  550-  561 (19.24/31.15)	FKSHAWGiLHTL
  679-  689 (24.55/ 7.37)	FTPHNWA.LHTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.84|      13|      19|     205|     219|       3
---------------------------------------------------------------------------
  205-  219 (20.59/15.83)	LRFPLKGllPYDKDL
  227-  239 (25.24/13.24)	LRYVLEQ..PYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      32|     296|     305|       5
---------------------------------------------------------------------------
  296-  305 (18.69/10.30)	IFFVLFQFAS
  329-  338 (19.45/11.03)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.82|      54|     619|     428|     483|       6
---------------------------------------------------------------------------
  428-  483 (87.96/51.63)	DYKIALLCN..AYSTNSECFTLpMGVLVE.TIYGNGNMRISLPGISCMASGSITPLpMN
 1048- 1104 (82.87/40.61)	DWRFNEFPNpaAHALHVTCVEL.MALTVPgKDVGNALLNVVLKSQPLVPRENITAW.MN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.98|      12|     710|     160|     171|       7
---------------------------------------------------------------------------
  160-  171 (23.19/13.38)	NLVSDFVDTFRP
  855-  866 (22.79/13.03)	NRVSDFVKENSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.32|      11|      19|     365|     375|      10
---------------------------------------------------------------------------
  365-  375 (22.61/14.54)	CIPVPDINKPQ
  384-  394 (21.71/13.63)	CIWIHLNRKAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.13|      30|     257|     497|     530|      11
---------------------------------------------------------------------------
  497-  530 (40.23/44.94)	IHSIATRVIKLAHAKsslALApALVETYSRLLVY
  760-  789 (52.89/40.88)	INQIGYRVLDRIGAR...ALV.AHVRTFADFLVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.20|      12|      20|     879|     893|      12
---------------------------------------------------------------------------
  879-  893 (16.71/21.11)	MSYHKKY.PekLYFeG
  902-  914 (21.49/12.31)	MQIQPSYlP..IYF.G
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27241 with Med23 domain of Kingdom Metazoa
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