<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27232

Description Uncharacterized protein
SequenceMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAATAAAAAAAAATPVAIAPQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Length527
PositionTail
OrganismOrnithorhynchus anatinus (Duckbill platypus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Monotremata> Ornithorhynchidae> Ornithorhynchus.
Aromaticity0.07
Grand average of hydropathy-0.253
Instability index37.10
Isoelectric point5.40
Molecular weight56764.71
Publications
PubMed=18464734

Function

Annotated function 
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central

GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central

GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27232
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     372.96|      40|      40|     335|     374|       1
---------------------------------------------------------------------------
  172-  207 (35.87/16.39)	..........PNKatVLRGHESE...........VFICAWNPVS.........dlL.ASGS.GDSTAR
  226-  263 (43.10/21.08)	HCirEGGHDVP....S....NKD...........VTSLDWNSDG.........tlL.ATGS.YDGFAR
  264-  293 (30.88/13.16)	I...WTEDGNLAS..TLGQHKGP...........IFALKWNKKG..........nY............
  294-  345 (44.42/21.93)	IL..SAGVDKTTI..IWDAHTGEakqqfpfhsapALDVDWQNNT..........tF.ASCS.TDMCIH
  346-  387 (63.35/34.20)	VC..RLGCDRPVK..TFQGHTNE...........VNAIKWDPSG.........mlL.ASCS.DDMTLK
  388-  438 (58.84/31.28)	IW..SMKQDTCVH..DLQAHSKE...........IYTIKWSPTGpgtsnpnsnimL.ASAS.FDSTVR
  442-  480 (50.14/25.64)	VE..RGVC...IH..TLTKHQEP...........VYSVAFSPDG..........kYlASGS.FDKCVH
  481-  522 (46.35/23.18)	IW..NTQSGTLVH..SYRG.TGG...........IFEVCWNARG........dkvG.ASASdGSVCV.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27232 with Med16 domain of Kingdom Metazoa
Unable to open file!