<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27230

Description Mediator complex subunit 24
SequenceMKLVNLKQAILQAWKERWSDYQWAINMKKFFPKGVTWDILNLAEALLDQAMIGPAPNPLILSYLKYAINSQMVSYSTVLTAISKFDDFSRDLCIQALLEIMDMFCDNLSCHGKAEECIGLCRALMSALNWLLRCSTFYTDKLKDMLDPVAGENHLSMCLQRLESMLSSTKNRALIHIAKLEEPASWTSVEQSLLRLAESISLLPSVQLRNQAEECVSLIRSIPSMLSVHSDQLQRNGFPTVHAVVMLEGTMNLTGDAQPLVEQMNTVKRMQRIPSHLFLLEVWKACIVGLIESPEGTEELKWTAFTFLKIPQALAKLKKLSPMEQDFNEDMKCAFEYLLKLTPLLDKADQRCNCDCVSLLLQECNKLGLLSDQNLENLVAKRTADREQAPRMKSAENSTIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIQLNEFTRHIGVESSKAANVRALLFDISFLMLCHVAQTYGSEMILSEGCPSGEMPFFESWMQTCMPGEGRVLNPDHPCFRHPDIAKVEALVALLNTSTEMKLAQTKWHEVCLSIPAAILEIHNAWENGVLSFEAIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDERDKSLQMIRQLGSPMFGDNTLQFYNERVIIMSSILDNMCAEVLQQTATQIKFSAPGSEPVPYIHRLPPKKPIKEVLRGAFSSTLEKGWVDSRTLHVFDTLLHMGGVYWFCNNLVKELLRETRLEFALRAVELLYAIFCLDMQQLTLTLLGHVLPSLLTDSAKWHMLMDPPGRALAKLSVWCAMTSYSTQNKGQPSPRQRKRHREDIEDYSSLFPLDDTQQSKLMRLLSSNEEEHSVQANPVDRPMNSSLSASQIHNISSKEPLNRVLANLFLLISSVLGAKTAGAQTQFVQWFMEECVESLELGGKGCILQFMPFSMVSELVKVSTLSSPKIVLAITDLTLPLGRRVAAKALTAL
Length988
PositionTail
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Amphibia> Batrachia> Anura> Pipoidea> Pipidae> Xenopodinae> Xenopus> Silurana.
Aromaticity0.07
Grand average of hydropathy0.001
Instability index45.32
Isoelectric point6.47
Molecular weight110559.75
Publications
PubMed=20431018

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27230
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.23|      19|     488|     355|     386|       5
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  214-  232 (34.24/12.31)	ECVSLIRSIPSMLSVHSDQ
  355-  373 (33.99/36.80)	DCVSLLLQECNKLGLLSDQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.38|      38|     701|      34|      71|      12
---------------------------------------------------------------------------
   34-   71 (65.52/38.61)	GVTWDILNLAEALLDQAMIGPAPNPLILSYLKYAINSQ
  738-  775 (66.86/39.54)	GVYWFCNNLVKELLRETRLEFALRAVELLYAIFCLDMQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27230 with Med24 domain of Kingdom Metazoa
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