<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27222

Description Mediator of RNA polymerase II transcription subunit 15
SequencePFLRSPVCFQVGQNSMPMMSSPSPVQQAQTPQSMPPPPQPSPQPGQPTSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPAAARTPQNFSVPSPGPLNTPVNPNSVMSPASASQSEEQQYLEKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRSPVFNHSLYRTFVPAMTAIHGPPITAQVIAPRKRKLEEDERQTIPNVLQGEVARLNPKFLVNLDPSHCSNNGTVHLICKLDDRNLPSVPPLELSVPADYPDQSPLWIDKQWQYGTVP
Length333
PositionTail
OrganismOrnithorhynchus anatinus (Duckbill platypus)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-0.608
Instability index89.47
Isoelectric point9.09
Molecular weight36614.59
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27222
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.64|      18|      19|      22|      40|       1
---------------------------------------------------------------------------
   16-   33 (32.32/ 8.66)	MPMMSSP..SPVQQAQTPQS
   34-   53 (33.33/10.93)	MPPPPQPspQPGQPTSQPNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.38|      20|      28|      57|      82|       2
---------------------------------------------------------------------------
   57-   79 (36.05/13.47)	SGPAPSPssfLPSP.SPQPSQSPA
   88-  108 (35.33/ 9.68)	SVPSPGP...LNTPvNPNSVMSPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.91|      23|      28|     149|     175|       3
---------------------------------------------------------------------------
  140-  167 (35.21/19.42)	DKNEdrkkdLSKMKSLLDILTDPSKRCP
  172-  196 (39.70/14.85)	QKCE...iaLEKLKNDMAVPTPPPPPVP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27222 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FLRSPVCFQVGQNSMPMMSSPSPVQQAQTPQSMPPPPQPSPQPGQPTSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPAAARTPQNFSVPSPGPLNTPVNPNSVMSPASASQSEEQQYLEKLKQ
2
124










Molecular Recognition Features






MoRF SequenceStartStop




1) LWIDKQWQYGTVP
321
333