<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27209

Description Mediator of RNA polymerase II transcription subunit 8
SequenceVQREEKQLEASVDALLNQVADLKTSLGSFIYKLENEYDRLTWPSVLDSFALLSGQLNTLNKVLKHEKTPPLRNQVIIPLVLSPDRDEDLMRQTEGRVPVFSHEVVPDHLRTKPDPEVEEQEKQLTSDAARIGADAAQKQIQSLNKMCSNLLEKISKEERESESGGLRQNKQTFNPADTNALVAAVAFGKGLSNWRPAVAGGPGQPGQPGTGGMMAGGSQQQQVPMAGAPGQQQQQQALLAGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR
Length271
PositionHead
OrganismOrnithorhynchus anatinus (Duckbill platypus)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.608
Instability index48.74
Isoelectric point6.51
Molecular weight29435.92
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27209
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.60|      12|      18|     188|     204|       1
---------------------------------------------------------------------------
  188-  204 (18.54/18.30)	GKGlsnwrPAVAGGPGQ
  209-  220 (24.05/10.70)	GTG.....GMMAGGSQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.78|      12|      18|      80|      97|       2
---------------------------------------------------------------------------
   80-   91 (21.03/22.06)	VLSPDRDEDLMR
   99-  110 (21.75/ 7.30)	VFSHEVVPDHLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.86|      10|      18|     222|     231|       4
---------------------------------------------------------------------------
  222-  231 (20.15/11.42)	QVPMAGAPGQ
  243-  252 (19.71/11.00)	QMAQAGQPGK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27209 with Med8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) CSNLLEKISKEERESESGGLRQNKQTFNPADTN
2) FSHEVVPDHLRTKPDPEVEEQEKQLTSDAARIGADAAQK
3) SNWRPAVAGGPGQPGQPGTGGMMAGGSQQQQVPMAGAPGQQQQQQALLAGVQMAQAGQPGKMPSGIKTNIKSASMHPYQR
147
100
192
179
138
271










Molecular Recognition Features






MoRF SequenceStartStop




1) GIKTNIKSASMHPYQR
256
271