<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27205

Description Prostate tumor overexpressed 1
SequenceMVRPRRAPYRSGAGGPLGGRGRPPRPLVARAVRSRSWPASPRGPQPPRIRARSAPPMEGARVFGALGPISPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYHPHAWLTQLSVPCPPQTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAVGPGGVNSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQVLQRNLEQEQQQRGVRQPGPRAAQPPPHPSCLLTTGL
Length426
PositionUnknown
OrganismMacaca mulatta (Rhesus macaque)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Cercopithecinae> Macaca.
Aromaticity0.08
Grand average of hydropathy-0.352
Instability index54.73
Isoelectric point10.75
Molecular weight47733.99
Publications
PubMed=17431167

Function

Annotated function 
GO - Cellular Component
nucleoplasm	GO:0005654	IEA:Ensembl
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27205
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     543.99|     145|     159|      65|     223|       1
---------------------------------------------------------------------------
   65-  223 (268.03/180.81)	ALGPispSspGLTLGGLAVsehrLSNKLLAWSGVLEWQEKR.RPYSDStaklKRTLPCQAY.......HPHAWLTQLSVPCPPQ...TTLGPLFRNSQLAQFHFTnRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVI
  229-  384 (275.97/155.14)	AVGP...G..GVNSGPVQI....VNNKFLAWSGVMEWQEPRpEPNSRS....KRWLPSHVYvnqgeilRTEQWPRKLYMQLIPQqllTTLVPLFRNSRLVQFHFT.KDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.17|      19|      20|      20|      38|       2
---------------------------------------------------------------------------
    3-   16 (19.68/ 6.12)	......RPRRAPYRSGAGGP
   20-   38 (38.41/18.85)	RG.RPPRPLVARAVRSRSWP
   42-   55 (22.07/ 7.75)	RGpQPPR.I.....RARSAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27205 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MVRPRRAPYRSGAGGPLGGRGRPPRPLVARAVRSRSWPASPRGPQPPRIRARSAPPM
1
57










Molecular Recognition Features






MoRF SequenceStartStop




1) MVRPRRAPYRSGAGGPLGGRGRPPRPLVARAVRSRSWP
1
38