<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27165

Description ATP-dependent DNA helicase
SequenceMDSNYDLLEELFNVELELQDVQDQIKNLLDRQEKLHERQSELKTLLEACKGSGSPVKDGASVAVENWSGPFDWDAQADDVRFNIFGISTYRANQREIINAVMSGRDVLVIMAAGGGKSLCYQLPAILRDGVALVVSPLLSLIQDQVMGLAALGIPAYMLTSTTSKEDEKFIYKALEKGDGDLKILYVTPEKISKSKRFVSKLEKCHHSGCLSLISIDEAHCCSQWGHDFRPDYKNLGILKTQFPDVPVVALTATATKKVQNDLMEMLHIPKCIKFVSTVNRPNLFYMVREKSSVGRVVIDEIAEYIQESYPNNESGIVYCFSRKECEQVAKELRERGISADYYHADMDVNARERVHLRWSNSKLQVIVGTVAFGMGINKPDVRFVIHHSLSKSMETYYQESGRAGRDGLPSECLLYFRPGDVPRQSSMVFYENSGLQNLYDIVQYCQSKRECRRNAFFRHFAEPLQDCNGMCDNCAFSTEVKEVDVSCLAKAMISLLQDMQDNDQRLTMLQMVDKMKVKNKDLGSDLRKEEIEHLVIQLIRDRVLKEEFQHTAYATNAYVTLGLLWKQVSHGKRIVKLEISTKVKTKTGNMKSSKRSLTSSGLELKLDELRKELSSTHGGIFPHSVLSTQQISILSAQKPTSILEAKTMIGKLKTEKYGSKILEEIAKYTETEQPENVPPDDSTLGEGQGSEKKPTKRLKTDEAQGSEKKPTKRLKTDEGQGSENRAPKRLKSNKAVVLIESSGDET
Length747
PositionUnknown
OrganismVitis vinifera (Grape)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> Vitales> Vitaceae> Viteae> Vitis.
Aromaticity0.07
Grand average of hydropathy-0.460
Instability index45.45
Isoelectric point6.97
Molecular weight84136.24
Publications
PubMed=17721507

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27165
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.55|      15|      15|     689|     703|       1
---------------------------------------------------------------------------
  689-  703 (30.83/16.31)	QGSEKKPTKRLKTDE
  705-  719 (30.83/16.31)	QGSEKKPTKRLKTDE
  721-  735 (26.90/13.45)	QGSENRAPKRLKSNK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.50|      16|      16|     630|     645|       2
---------------------------------------------------------------------------
  630-  645 (26.29/16.25)	Q.QISILSAQK.PTSILE
  647-  664 (16.21/ 7.33)	KtMIGKLKTEKyGSKILE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.12|      25|     124|     305|     330|       3
---------------------------------------------------------------------------
  305-  330 (44.37/34.25)	YiQESYPNNESGIV.YCFSRKECEQVA
  431-  456 (43.75/28.80)	Y.ENSGLQNLYDIVqYCQSKRECRRNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.77|      56|     155|      16|      74|       4
---------------------------------------------------------------------------
   16-   74 (87.39/60.36)	LELQDvqDQIKNLLDRQEKLhERQSELKTLLEACKGSG..SPVKDGASVAVENWSGPFDWD
  175-  232 (96.38/56.42)	LEKGD..GDLKILYVTPEKI.SKSKRFVSKLEKCHHSGclSLISIDEAHCCSQWGHDFRPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.42|      15|      15|     493|     507|       6
---------------------------------------------------------------------------
  493-  507 (24.93/15.80)	MISLLQDMQDNDQRL
  509-  523 (24.49/15.41)	MLQMVDKMKVKNKDL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27165 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EEIAKYTETEQPENVPPDDSTLGEGQGSEKKPTKRLKTDEAQGSEKKPTKRLKTDEGQGSENRAPKRLKSNKAVVLIESSGDET
664
747










Molecular Recognition Features






MoRF SequenceStartStop




1) SEKKPTKRLKTDEAQGSEKKPTKRLKTDEGQGSENRAPKRLKSNKAVVLIESSGDET
691
747