<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27119

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSSETQIANILNDILKVEAIEEAFSCVLVHHPKKETDKVAAWHQELRTAMTGLTKEQQEAAVRQFLSIAAAMTNHRRLQLLLSLLENLVHSNFLPARLVCECILSCDKLQYQLEDFWVECFVLIKHILGGVDYKGVREIMKGCKEKAQTIPARLDASVQPQLKALENVIEFIFDRNACLLPGYFIVNEIQKAYPDGKNWPHWKLAKLLSDFVESFRHTAQMVSIVGHSKMLPVVEHTGYADYLINPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCVVLEEQLVELVILAMERSENETLPAEGMDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFLPVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQTEPGTNIHRPIPHTLKVHHEFLQHLVMPNASLCMGSDYRIALLCNAYSTNQEYFSRPMAALVDTILGTQKNQQQQPLQNLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSIVTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKTLVSAESEELNRALVLTLARSMHVTGTGADSLSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMNNENDIIAHFSVPGTPPLFLCLLWKMILETDRISPIVYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDRLVLCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSGGPSQYQNLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYEKKLRDRPLLKRRLVSAVLGSLREIRAPGWALSEAYQMYMTRFNDDAVSWVPELDYYIRLVQRIVETMSGTAHFPATDWRFNEFPNPAAHALYVTCVELMALPVAPDAVANFLLDVVAKGYTVVPSDEIHLWINCVGLLLAALPECYWSALHKRLLETISSPGLVNWQYNNLTPFQMFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLARFNAERPHCVVELAVCLYEMLERVDHTQTTLNYMDSICDLLYHIKYMFVGDMTKNEVECIIRRLRPALQMRLRFIAHINIDEIHTS
Length1357
PositionTail
OrganismAcromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus echinatior)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Acromyrmex.
Aromaticity0.09
Grand average of hydropathy-0.031
Instability index46.61
Isoelectric point6.73
Molecular weight155542.95
Publications
PubMed=21719571

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27119
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.73|      34|     148|     454|     495|       1
---------------------------------------------------------------------------
  454-  495 (56.85/58.69)	IHRPIPHTLKVH...........HEFLQHLVMPNaslcmgsdYRIALLCNAYS
  603-  647 (54.88/37.50)	ISQLLPTVFKSHawgtlytllemFSYRMHHIQPH........YRVQLLSHLHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     471.51|     162|     260|     810|    1016|       2
---------------------------------------------------------------------------
  810- 1016 (238.07/341.60)	WkmILETDRISPIVYKILERIGAralSAHLrKFCDYLVFEFANSVGGQHVNKCVDTIN.............DMIWK.YNIVTIDRLVL...ClalrtqegneaqvcffiIQLLLLKAAE.....FRNRVQEFVkeNSPehwKQSNWHEKHLAFHRKFPEKFAPEGIME.QTS............GGPSQyqnlpvyfgnvcLRFLPVFdivVHRYLEipPVIKSLEILLE..HL.G.CLYKFH.DRP
 1077- 1278 (233.43/204.98)	W..VPELDYYIRLVQRIVETMSG...TAHF.PATDWRFNEFPNPAAHALYVTCVELMAlpvapdavanfllDVVAKgYTVVPSDEIHLwinC.................VGLLLAALPEcywsaLHKRLLETI..SSP...GLVNWQYNNLTPFQMFNFNITHNSLLEnKYSymlalahsvwhhAGVGQ............ITTMPQF...IKEKLQ..PVVSSEEQLIYacHLiGpTLARFNaERP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.35|      33|     273|     387|     419|       3
---------------------------------------------------------------------------
  184-  215 (45.69/26.47)	..F.IVNEIQKAyPDGKNWPHWKLAKLLSDFVESF
  254-  276 (33.20/17.12)	LKFsLKGNLPYD.P...........DLLKPQTELL
  387-  419 (58.47/36.03)	LQF.ISGSIQRN.PLSNFLPVLKLYDLLYPEKEPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.20|      33|     273|     497|     546|       5
---------------------------------------------------------------------------
   52-   85 (49.23/19.77)	GLTKEQQEAAVrQFLSIAAAMTNHRRLQLLLSLL
  514-  546 (57.97/25.93)	GTQKNQQQQPL.QNLQNNAALANGPTTPLSMSIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.52|      45|     582|     126|     176|       6
---------------------------------------------------------------------------
  126-  176 (71.28/60.67)	HILG.GVDYkgvreiMKG..CKEKAQTIPARLDAS.VQPQLKALENVIEFIFDRN
  714-  762 (66.24/43.61)	HVTGtGADS......LSGtwCKELLNTIMQNTPHSwANHTLQCFPPVLSEFFQQN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27119 with Med23 domain of Kingdom Metazoa
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