<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27115

Description Mediator of RNA polymerase II transcription subunit 29
SequenceMPVVRWRRFPPDAMRDSTRSFVAVQADSSTKSPMRSRLTLRHDSQIKMNIPPIQQPGAMGVGQMGQSVNPQLPQNQQQAQQTQQQVQQQQQQQQQQQQQQQQQQQTQDKLDNISKVKSLVGPLRESLAIALKTAAQTLHQNSLVDVGTMKGIEQPDHRFNKNMEEFYSICDQIELHLKTSVECLSQHSSSVRYLPMSVITTRTDTVSTQEGPALSYPQFLMTVRAQVAYAREIHDTLMSHARAISSGEQS
Length250
PositionTail
OrganismAcromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus echinatior)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Acromyrmex.
Aromaticity0.04
Grand average of hydropathy-0.752
Instability index76.55
Isoelectric point9.20
Molecular weight28278.54
Publications
PubMed=21719571

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27115
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.58|      15|      15|      74|      88|       1
---------------------------------------------------------------------------
   74-   88 (29.02/ 9.02)	QNQQQAQQTQQQVQQ
   90-  104 (29.56/ 9.31)	QQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.43|      13|      15|      19|      31|       2
---------------------------------------------------------------------------
   19-   31 (21.16/15.09)	RSFVAVQADSSTK
   35-   47 (22.27/16.24)	RSRLTLRHDSQIK
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27115 with Med29 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MPVVRWRRFPPDAMRDSTRSFVAVQADSSTKSPMRSRLTLRHDSQIKMNIPPIQQPGAMGVGQMGQSVNPQLPQNQQQAQQTQQQVQQQQQQQQQQQQQQQQQQQTQDKLDNISKVK
1
117

Molecular Recognition Features

MoRF SequenceStartStop
1) MPVVRWRRFPPDAMRDSTRSFVAVQ
2) MRSRLTLRHDSQIKMNI
1
34
25
50