<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27106

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMETKVTSKTSSLKALLLRAWRERWTDLQWGINIKTILPRGVSGDVYNLADYILQQALVGPGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCIVSLLEFLESIQVGITCRGKPEEDLLAAAVLSIVHWLLQCYLHTLTKTPQSNPLTPHPSELVDKPASILQQMLNSDFLCAMMYLAKYDDKDLYIEVVKKCQEIETLLKTSTQKSVVPIEDSLKKLCNLEIESLCPEKTKMESITHCLQPLFAVQVLLNPSTETTVFVNQLLMVQRLKSYTNARLYCEIIRACLMCLHNVTGTFKESQWGAFTFLKVPHILKELHVTNLNGDEKFEYSQDILDAFELLLQFTPLLDIMDTTCSCNYVECLLNELQKVNLVTEKQAKQIGARREGATTTSSIPKVIVRAGQTLNGILRTLNADYAKIQEGLLSVLYQVLTGKSFELMLAVATVEGELKTFVTKLIKFNECSKQINEPVPDKTAATRAMLFDVSFLMLCSIVQTYGSDVVLEEGGDSFFEQWVRECMPERNKLKSPQRMLQSVDSARVDALLAQINSPDPDFKSSNLKWHVACQSAMGAVKELLCAWESGVLGAGDVKRALDGLRATACCLPVCAAAWLCAYMSITHQDALLKPMNMVQHFLTPLSGDEMQDNLKDRSSLMVQIIRKMQYDVHPPTQSKTKVLSMSHSIISRQPILEQLESVWQNINQRGWINIQATQSLESLLNTGGSLWFVTNIVKEVLKYRYQEELDQAVDLAFAVFHLDIENCTLDLINHIIPQYLHNSMQSDELVEPQSSILAKLCVYCIFSTLEYNNSNPYRGNSRKRVRRDLDTDDLDALGVSNKLLRLNETGENVPMFSSQSPQAQGSSNGQKSVVILRDPLMTALNNLFTIFAFLAGRDGEVSQQTHFILQFLRLMVQCGKDRTRIVLQGMSQTLVPCLLKALPELFTTDILLRLYDIQTMIGRKATARDLCMLRNINLKPTK
Length978
PositionTail
OrganismAcromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus echinatior)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Myrmicinae> Acromyrmex.
Aromaticity0.07
Grand average of hydropathy-0.044
Instability index46.57
Isoelectric point6.57
Molecular weight110207.74
Publications
PubMed=21719571

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27106
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.95|      14|      83|     139|     173|       1
---------------------------------------------------------------------------
  159-  172 (23.90/17.50)	ELVDKPASILQQML
  784-  797 (24.05/18.75)	ELVEPQSSILAKLC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     524.02|     181|     277|     233|     463|       2
---------------------------------------------------------------------------
  233-  447 (269.78/208.96)	C.PEKTKMESITHCLQPLFAVQVllnpstettvfvNQLLmvQRLKS....YTNARLYCEIirACLMCLhnvtGTFKE..SQW..GAFTFLKVPHILKELH....................................VTNLNGDEkfeySQDIL.DAFELLLQFTPLL..DIMDTTCSCNYVECLLNEL...QKVNLVTEKQAKQIGARregatttSSIPkviVRAGQTLNGILRTLNADY..AKIQEGLLSVLYQVLTGKSFELMLAV
  522-  755 (254.25/125.15)	CmPERNKLKSPQRMLQSVDSARV............DALL..AQINSpdpdFKSSNLKWHV..ACQSAM....GAVKEllCAWesGVLGAGDVKRALDGLRatacclpvcaaawlcaymsithqdallkpmnmvqhfLTPLSGDE....MQDNLkDRSSLMVQIIRKMqyDVHPPTQSKTKVLSMSHSIisrQPILEQLESVWQNINQR.......GWIN...IQATQSLESLLNTGGSLWfvTNIVKEVLKYRYQEELDQAVDLAFAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.02|      26|     700|      99|     124|       3
---------------------------------------------------------------------------
   99-  124 (45.56/31.08)	CIVSLLEFLESIQVGITCRGKPEEDL
  800-  825 (47.47/32.69)	CIFSTLEYNNSNPYRGNSRKRVRRDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.21|      17|     653|     211|     227|       4
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  211-  227 (30.86/17.31)	QKSVVPIEDSL.KKLCNL
  866-  883 (25.35/13.05)	QKSVVILRDPLmTALNNL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27106 with Med24 domain of Kingdom Metazoa
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