<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27093

Description Uncharacterized protein
SequenceMAANYWLSSHANNHILTRHDLRTSPGRAIDLKFASEREIACVNIWSCNVIHKLAKRLNCRQIVTATAVTYFRRFYVKNAIADTDPCLVASACMYVATKVEEAPCHIKTVVEAARFVFAEYPALGAFPTDAAVLAEMEFYLIEDLDFHLIIWHPYRDLAHFTGREDSAVPKDASEKLSEWVPAAGSNFYDEYRRECDRQASMLDLSDEALQMAWFIINDTYRTDIILLYPPYIIALASIYITVVLQPHPSLRAIKQLPPPVHLTSTNTSNNTSNESSAANSIRKQSLPPSQQTVNPLDFFAHFPLSMSLVLELVQEIVASYELWNRLENPLLPIQRPPDNPADLPSGLASTRLNQPYNNSTNARPIHESSESSPASKAAGLMAAAKTGDKAADERVVEVLVRMRKEREADLG
Length411
PositionKinase
OrganismMelampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf rust fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Pucciniomycetes> Pucciniales> Melampsoraceae> Melampsora.
Aromaticity0.09
Grand average of hydropathy-0.185
Instability index53.23
Isoelectric point5.77
Molecular weight46014.79
Publications
PubMed=21536894

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27093
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.80|      29|      31|     318|     347|       1
---------------------------------------------------------------------------
  318-  347 (51.26/37.00)	ASYEL...WNRLENPlLPIQRPPD.NPADLPSGL
  348-  380 (40.54/24.07)	ASTRLnqpYNNSTNA.RPIHESSEsSPASKAAGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.72|      13|      28|     249|     263|       2
---------------------------------------------------------------------------
  249-  263 (20.33/18.48)	SLRaiKQLPPPVHLT
  280-  292 (24.39/15.01)	SIR..KQSLPPSQQT
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27093 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LPIQRPPDNPADLPSGLASTRLNQPYNNSTNARPIHESSESSPASKAAGLMAAAKT
2) QLPPPVHLTSTNTSNNTSNESSAANSIRKQSLP
331
255
386
287

Molecular Recognition Features

MoRF SequenceStartStop
1) SKAAGLMAAAKTGDKAADERVVEVLVRMRKEREADLG
375
411