<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27086

Description Uncharacterized protein
SequenceMRLYRARRDRERVTIQEQYAILGFISSGTYGKVYKGQPRALVDSHLPGQNSREARGDLVAIKKFKPDREGEVNYTGISQSACREIMLNREIQHENVASLKQVMLQDKSIYLVFEYCEHDFLQIIHHHSQSRSNIPESTLKSLLWQLLNGVNYLHANWIVHRDLKPANILVTDRGVVKIGDLGLARSYHSPLQSLYSSDKVVVTIWYRSPDLLLGARHYTPSVDIWSVGCIMGELLYLRPMFKGEEAKPEPHSKKGGSGVPFQRDQLHKIFDILGLATKEEWPSIVHLQEYPHLARTTNSLRHWYNARTTSFRSSPAAQNEGYDLLCQLLRYDPSSRITAKESLTHKYFSLSFPPLPSLNCFDGQHGVVYPVRRVTPDDSDPKMSVAGPAAPSGGGAGLLGAKSTYNPLSALHTASRPGTAGHDGLPVRSSKRARYD
Length436
PositionKinase
OrganismMelampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar leaf rust fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Pucciniomycetes> Pucciniales> Melampsoraceae> Melampsora.
Aromaticity0.09
Grand average of hydropathy-0.456
Instability index49.99
Isoelectric point9.33
Molecular weight49041.15
Publications
PubMed=21536894

Function

Annotated function
GO - Cellular Component
euchromatin	GO:0000791	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:EnsemblFungi
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27086
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     127.59|      27|     107|     183|     209|       1
---------------------------------------------------------------------------
  183-  209 (49.42/29.48)	LARSYHS....PLQSLYSSD...KVVVTIWYRSP
  293-  315 (39.87/22.51)	LARTTNS.....LRHWYNAR......TTSFRSSP
  343-  376 (38.30/21.36)	LTHKYFSlsfpPLPSLNCFDgqhGVVYPVRRVTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.25|      21|     377|      37|      57|       3
---------------------------------------------------------------------------
   37-   57 (37.79/18.18)	QPRALVDSHLPGQNSREARGD
  416-  436 (38.46/18.61)	RPGTAGHDGLPVRSSKRARYD
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27086 with CDK8 domain of Kingdom Fungi

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