<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27073

Description Uncharacterized protein
SequenceMTGSQRQGPHRSNTNTSEHSLGRIQQHQSLNNTANNISESTFINNSQLASSLAYPNPLLGLSQFRDRPDSRQQMQSAMLDDSDVTAISTASQRNPYPMTGSAQRLRQMPQFQPMLQSGVQQHIQLSQSGSSVSMQAAHAPQLNPKLQPQILQPQLLQHIQQQQFLQQQQHQNLFQQQHQEPSQQHLKRFQKQNITPPLFVSDSSVHGLKPLHKYEYRLPSDRLLSRSGGSDYVDVYLQRHGQPEDKLDETTVKAGYTDKSPVQNETLSVFESIHIYDHLSRKNVFQDMVKFASTVLAAQSQVTFPKESQFTISRRTGTSSKTYDNWIDDLFGNIPFSELSKSVPFGLKLDKLLESLQQKQVSLVRATWAIKMIGVTDLASSSRLSRVDSHLDASFSWTSIVIAYIQKQINEVSLSAVNTPQISQVRNQKRTQSKEAIAAAAEAAASKHISPKQRHHFISRWDYLMRLCAKQYEEGLLDQGSFLKKSLEIFKMCNFSQTMFAVTLISMFVLEIGRSRALMRLLVSICLKKLKKLKLHISTSDFAKEQYNQLVILLQRGYRCAPDTFVSTKLWVNFEEFLTVVFADEHQTRMEVESRNNWLISSAPLTLCASESLNVLFRTLGYWTNYSQIYQTWDAFFDGFTDISIHLRHIFNWALADSRPSQDSRAFIAARLVSEWYKNMLNDNLTKKNHHSLLSMNFAKLFYKLLDKLIATLPSGQDEQHRLFLLFSQLEQLRVFSIRQYAQRLVSRGDLDSSSNTSEKFKCFLQGYPLRIAELVQNCQLYHKNDVNLANDSDNDFCIQSVLELIVRTDTESRKQDVLHFENIKKQIIAVLPRIYISGDKVDTLRDRLVQDMPKDRALAWPNMKLKQNLISLVPIWRIRLSIWLKKCVVQFIVKAQEIGINNWKTVSTPGNSTLNDRQLATVIWILETLRDYPSLLEILMWLINKTTERNIYRSIVFALERHQLVFHAMGCSQLIFDHLFEKHQTLRKRGTGLDPHILRHLFSLLTHKLCEMDFEERKKLESDRALPLKRGTSKEIPLEFRDLRDAKDDRQSITNAASSLIWRFQDMREALARLFKYSLILLSRQSSIMQKDDFRRRVTLTVEVLREVADRNPSLQASIIDHYRDTYVTSKPFTVMTPGTELLGGIDNMASTWSISMIVQLITSRCCPLQRFLDEVVDPIISRAKANIDLLKSVYFTNLISNMVYLLSVICISTESVSLTPQLILTLQQYQYLERLRVVDMHTPAYLSRILHILQSLAFIRSRLTSTSAAVDIASNEQLLSGIQVLLTYVLERPGWFKHACITDQSWISFDLARLFTDAKNLFSQDTLALDMVLQSTHVVFKALWDTHTFDGYTENTVEAPFNINAFETCFERICRHSNACNRDRCQYLLTLTLELLHLHQSIHASGVTAVSSFSQSVSVDSIAASRQNMAEAYSKCWDRLVDVCFKEVLGRNSTSLSHLLPKMRWEFLKRLVVRSQQLMESVHSLLSTTPLKEFNLAGTNIALDADSQQHLVVNTASIKCFGEFTSKLGVYMCHRLKEVRKAKSSGKTAAKQTEDAYLADISVLAAFILRDLLWFQENIKVFDLMVDNEISFGKAHQLSTAVSSTDLPPSQLQDQVMLAQIQEILIARLTLVKTLAPVIMENPIRFQIVLLAQSLMKLLVSKLVTNTIGTSHLFQITLDVVSWFMEEIPKDLSKGLFAWLVKNRQEFSLPSPAGDRVNRILPFVDRNRLVSNLIFRSSGFNESLHELGTATSSSASSTPIWKPSQVSASVSTQSTGMSASITSPTPSASNTPHLARAPIVTSDSKHSTKPASFLKVDQHYFLPWKWLEDPGDVVLQQQPPAPSMCWANPNTIAPLNNTPISLTSFGAKVLHPMEPAYIQLHKQGWTLPDVGSRVSDNTALMELTNFSDEESVVEVVMTSSTVTAASTQPTPVAHVDMPQHTTFDAMDIDVNPNHQAGIMDVKIHSGSLKPAVTKGSRIPTKRKSTDTTTTGITKAIKKHN
Length2002
PositionKinase
OrganismBatrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid fungus)
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Chytridiomycota> Chytridiomycota incertae sedis> Chytridiomycetes> Rhizophydiales> Rhizophydiales incertae sedis> Batrachochytrium.
Aromaticity0.08
Grand average of hydropathy-0.232
Instability index45.20
Isoelectric point9.02
Molecular weight227359.86
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27073
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     356.80|      92|     143|     193|     314|       1
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  193-  284 (155.16/96.42)	NITPPLFVS..DSSVHGLKP....LHKYEYRLPSDRL.LSR.S.......GGSDYVDV..YLQRHGQPEDKLDE....TTVKAGYTDKSPVQNETLSVFESIHIYDHLSRKNV
  333-  431 (116.74/109.59)	NI.PFSELS..KSVPFGLK.....LDKLLESLQQKQVsLVR.AtwaikmiGVTDLASS....SRLSRVDSHLDAsfswTSIVIAYIQKQ.INEVSLSAVNTPQISQVRNQKRT
 1858- 1937 (84.90/43.10)	NNTPISLTSfgAKVLHPMEPayiqLHKQGWTLPD..V.GSRvS.......DNTALMELtnFSDEESVVEVVMTS....STVTAASTQPTPVAHV...................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     326.52|     107|     143|    1439|    1580|       2
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 1439- 1548 (168.38/100.87)	WDRLVD..VCFKEVlGRNSTSLSHL.LPKMRWEfLKRLVVRSQQLMESVHSLLST.TPLKEFNLAGTNIALDADSQQHLVVN...TASIKCFGEFTSKLGVyMCHRLKEVRKAKSSG
 1584- 1697 (158.15/93.20)	FDLMVDneISFGKA.HQLSTAVSSTdLPPSQLQ.DQVMLAQIQEILIARLTLVKTlAPVIMENPIRFQIVLLAQSLMKLLVSklvTNTIGTSHLFQITLDV.VSWFMEEIPKDLSKG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.88|      18|     143|     297|     314|       3
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  297-  314 (31.72/18.09)	AAQSQVTFPKESQFTISR
  443-  460 (33.16/19.25)	AAASKHISPKQRHHFISR
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.41|      31|     143|    1247|    1279|       5
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 1247- 1279 (47.68/33.48)	YL....SRILHILQSL.....AFIRSrlTSTSAAVD.IASNEQ
 1389- 1429 (36.74/19.44)	YLltltLELLHLHQSIhasgvTAVSS..FSQSVSVDsIAASRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.61|      32|      34|      91|     124|      11
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   55-   83 (43.41/24.14)	....PNPLLGL.....SQ.FRDR.PDSRQ.QMQSAMLDDSD
   91-  124 (57.64/42.42)	SQrnPYPMTGS.....AQRLRQM.PQFQP.MLQSGVQQHIQ
  126-  160 (34.56/17.91)	SQ......SGSsvsmqAAHAPQLnPKLQPqILQPQLLQHIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.18|      51|     239|    1072|    1136|      12
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 1072- 1136 (68.64/77.75)	LARLFKYSLILLSrqssimqKDDFRRRVTL..TVEVLREVADRNpslqasIIDHYRDTYVTSkPFTV
 1313- 1365 (84.55/57.06)	LARLFTDAKNLFS.......QDTLALDMVLqsTHVVFKALWDTH......TFDGYTENTVEA.PFNI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27073 with Med12 domain of Kingdom Fungi
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