<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27029

Description Uncharacterized protein
SequenceMPASLELTHSSLYASFINSIAWSLSLHLTKRHGAIPLGKRTFFTAADSDMSPGGTSTSVISTLDIELSQSGKVVISLRSRSQPGISQLSEGLGVSSIGELRLHDNIWLAPAGTIARYIGIGGSEYALGTGNSYHSNNMHSSRNGFSSEGQDPWKLAVCSWLERTGVPIEISDNMRWVQVEVVTRHQRLGQGKATGTRRIYWPAQLCFKKARFPTSSPIQGAETLSRDSLGPLQYARQWLKCSVPRDEVLSRNAPSDVAQHPEQHPRSETLASPDGIDIPNTTESMARAFLCPDFHPATVYPTPPGGTLGFGQLSSDHSGGQYPLELSHISREEPDANITESLNPNTRNLLEATSPGLGTGTGMYDTADDDLFEEMDDNFDNKGITEADFNFFDEPGLSDTNLDVDSGNPSHNFVISDHPTAESKPDLEMSESLASLEPVPPTESHGMETPMLDNLVEEGANQGQSEIKSSQPTARAADTDRNTERPISPPLSPSGVKRILFSSPKGSSEKPKNTINSATKLPVEASNQSGQHKGRYDAVSFRHGLDFSDRKYGIDGRFWFLPDHKTFNYNADSHTTKIPMVNDSSAPVYKLGQHVYPRKINERLDGADSERCSSSTSSTSSVSGDHYEQAGFNKMRPVDPIDNRLRRGDLEEIFSVSSSLQSPGFNVRKRYSTHSDLEEDVLLAGLIYPATDWLLSKYFTAFEPSIRSALCGRDETLHVAQLLVDQITQSTLTHKTEIAYEENEKDIWQASIDDINALGQSRRPSLKSYASISDIGPSQQIKDTTGGAIVNLRPPHMHIRRGNCSLEVLPTAISFWETFGLEPLKGKKDIISYCLHPVSMQESANAFLDRLGLTYLGANLGTFARHGSAKGLVPWSLSQDKLDYTSIMRRLQHICESLGT
Length900
PositionKinase
OrganismTrichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Onygenales> Arthrodermataceae> Trichophyton.
Aromaticity0.07
Grand average of hydropathy-0.523
Instability index54.24
Isoelectric point5.54
Molecular weight98771.66
Publications
PubMed=22951933

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27029
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     199.79|      51|      83|     332|     386|       1
---------------------------------------------------------------------------
  280-  328 (45.43/17.79)	.....NTTESmaraflcpdFHPAT...VYPTPPG.GTlGFG..QLSSDHSGGQYPLELSH.....
  332-  386 (80.50/45.55)	EEPDANITES.........LNPNTrnlLEATSPGlGT.GTGMYDTADDDLFEEMDDNFDNKGITE
  423-  466 (73.86/32.98)	SKPDLEMSES.........LAS.....LEPVPP..TE.SHGMETPMLDNLVEEG....ANQGQSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     198.83|      62|     266|     214|     277|       2
---------------------------------------------------------------------------
  214-  277 (102.11/56.65)	TSSPIqgAETLSRDSLGPLQYARQWLKCSVPRDEVLS.RNAPSDVAQHPEQH.PRSETLASPDGID
  483-  546 (96.72/48.50)	TERPI..SPPLSPSGVKRILFSSPKGSSEKPKNTINSaTKLPVEASNQSGQHkGRYDAVSFRHGLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.77|      35|      36|      19|      54|       4
---------------------------------------------------------------------------
   19-   54 (57.12/43.10)	SIAWSLSLHLTKrHGAIPLGKRTFFTAADSDMSPG.G
   58-   93 (51.64/33.58)	SVISTLDIELSQ.SGKVVISLRSRSQPGISQLSEGlG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.40|      25|     720|     130|     155|       6
---------------------------------------------------------------------------
  130-  155 (45.40/26.69)	GNSYHSNNMHS.SRNGfSSEGQDPWKL
  852-  877 (42.00/20.26)	GLTYLGANLGTfARHG.SAKGLVPWSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27029 with Med13 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KGITEADFNFFDEPGLSDTNLDVDSGNPSHNFVISDHPTAESKPDLEMSESLASLEPVPPTESHGMETPMLDNLVEEGANQGQSEIKSSQPTARAADTDRNTERPISPPLSPSGVKRILFSSPKGSSEKPKNTINSATKLPVEASNQSGQHKGRYDAVS
2) LSRNAPSDVAQHPEQHPRSETLASPDGIDIP
3) YPTPPGGTLGFGQLSSDHSGGQYPLELSHISREEPDANITESLNPNTRNLLEATSPGLGTGTGMYDTADDDLFEEMDDNFD
382
249
300
540
279
380










Molecular Recognition Features






MoRF SequenceStartStop




1) TEADF
2) VKRILF
385
496
389
501