<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26984

Description Uncharacterized protein
SequenceMTAAPPSPQQIRDRLLQAIDPQSNIRNMVAVQEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEATLRGLAGATGSANGGAHNCRPEAGAAGPPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNLSPLPTNGISGSPESFPGSLDGSGHAGPEGSRLEHSENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQTKAVLLQQLDRVDETPGPPHPKAPPRCSFSPRNSRHEGSFARQRSPYTYKGSVPSPSQRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLSGPGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKANLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHGPPTDLPGLSREVTQDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length599
PositionUnknown
OrganismSus scrofa (Pig)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Suina> Suidae> Sus.
Aromaticity0.04
Grand average of hydropathy-0.910
Instability index59.84
Isoelectric point9.48
Molecular weight65604.89
Publications

Function

Annotated function
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central
GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP26984
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.94|      16|      18|     120|     135|       1
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  111-  126 (27.96/14.24)	CRPEAGAAG.PPKSIHD
  127-  143 (21.98/ 9.45)	LKNRNDIQRlPGQRLDR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     434.10|      95|      96|     181|     275|       4
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  181-  268 (150.25/55.02)	.......................PTNGISG......SPESFPGSLDG.SGHAGPEGSRLEHSENDKHSGKIP...................INAVR.....PHTSSP..GLGKPPG.PCLQTKAVLLQQLDRVD..ETPGPPHPKAP
  269-  365 (110.98/38.84)	PRCSFSPrnsrhegsfarqrspyTYKGSVP......SPSQRPQSLDA.TQVPSP....LPLAQ....PSTPP......................VRrlellPSAESPvrWLEQPEG.........H.QRLSGPG..CKAGLP.PAEP
  368-  470 (69.61/21.80)	PRAGFSP......dsskadsdaaSSGGSDSkkkkryRPRDYTVNLDGqVAEAG...................vkpvrlkerkltfdpmtrqIKPLT.....Q..KEP..VRADSPV.HTEQPRT....ELDKPE..AKANLQSP...
  480-  561 (103.26/35.66)	.......................SRNEIIQ......SYLSRQSSLLS.SSGAQTPGAHHFMSEYLKQEESTR...................RGARK.....PHVLVP..H.GPPTDlPGL.SREVTQDDLDRIQahQWPG.......
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP26984 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) HQNEATLRGLAGATGSANGGAHNCRPEAGAAGPPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNLSPLPTNGISGSPESFPGSLDGSGHAGPEGSRLEHSENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQTKAVLLQQLDRVDETPGPPHPKAPPRCSFSPRNSRHEGSFARQRSPYTYKGSVPSPSQRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLSGPGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKANLQSPFEQTNW
2) RQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHGPPTDLPGLSREVTQDDLDRIQAHQWP
88
491
476
560

Molecular Recognition Features

MoRF SequenceStartStop
1) KKKKRYRPRDYTVNLD
2) QIRDRLLQAID
3) RRLELL
392
10
327
407
20
332