<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26944

Description Uncharacterized protein
SequenceMTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEAALRGLGGGTGSANGGAHNCRPEAGAAGTPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNSSPLPTNGIGGSPEGFPGTLDGSGHSGPEGGRLEHGESDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQTKAAVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQRSPYTPKGSMASPSPRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLAGQGCKVGLPPAEPILPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHSAPTDLPGLNREVTQDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length599
PositionUnknown
OrganismCanis lupus familiaris (Dog) (Canis familiaris)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Canidae> Canis.
Aromaticity0.04
Grand average of hydropathy-0.890
Instability index58.40
Isoelectric point9.49
Molecular weight65252.49
Publications
PubMed=16341006

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26944
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     423.64|      98|      98|      96|     193|       1
---------------------------------------------------------------------------
   96-  184 (150.74/64.48)	.......................................................GL....GGGTGSANGG..AHN.............CRPEAG...........AA.GTPKSIHDLK..NR...NDIQ.RLPG..........QRLDRLGSRKRRGDQRDLGH.........PGPPPKVS....KASHD.SLVPNSSP..LPTNG
  185-  295 (99.66/40.00)	IGGSPEGFP................................................gtldGSGHSGPEGGrlEHGesdkhsgkipvnaVRPHTS...........SP.GLGKP...................PGpclqtkaavlQQLDRVD..ETPGP....PH.........PKGPPRCSfsprNSRHEgSFARQRSP..YTPKG
  296-  452 (102.99/41.60)	SMASPSPRPqsldatqvpsplplaqpstppvrrlellpsaespvrwleqpeghqrLA....GQGCKVGLPP..AEP.............ILPRAGfspdsskadsdAA.SSGGSDSKKK..KRyrpRDYTvNLDG..........Q.VAEAGVKPVRLKERKLTF.........DPMTRQIK....PLTQK.EPVRADSP..VHTE.
  460-  541 (70.25/25.91)	..........................................................................................KPEAK...........ASlQSPFEQTNWKelSR...NEII.QSYL..........SRQSSLLSSS..GAQTPGAHhfmseylkqEESTRRGA....RKPH..VLVPHSAPtdLP..G
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26944 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQNEAALRGLGGGTGSANGGAHNCRPEAGAAGTPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNSSPLPTNGIGGSPEGFPGTLDGSGHSGPEGGRLEHGESDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQTKAAVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQRSPYTPKGSMASPSPRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLAGQGCKVGLPPAEPILPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGV
2) PVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKASLQSPFEQTNW
3) QSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHSAPTDLPGLNREVTQDDLDRIQAHQWP
88
417
492
415
476
560










Molecular Recognition Features






MoRF SequenceStartStop




1) IRDRLL
2) RLKERKL
3) SKKKKRYRPRDYTVNLDGQV
4) VRRLELLP
11
419
391
326
16
425
410
333