<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26916

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAVNMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHCLLKLGEILANLSNHQLRSQAEQCGTLIRSIPTMLSVHSEQLHKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFILEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNTAFEFLLKLTPLLDKADQRCNCDCTNFLLQECSKQGLLSEASMNNLMAKRKADREHAPQLKSDENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHRSEESTKAASVRALLFDISFLMLCHVAQTYGSEVILSESNTGGEVFFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEIKLVQMKWHEACLNISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSVFCLDMQQATLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length989
PositionTail
OrganismBos taurus (Bovine)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Ruminantia> Pecora> Bovidae> Bovinae> Bos.
Aromaticity0.07
Grand average of hydropathy-0.001
Instability index47.54
Isoelectric point6.49
Molecular weight110428.23
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26916
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.05|      47|     185|     704|     757|       1
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  704-  757 (70.52/60.85)	KRPIKEVLTDIFakVLEKGWVDSRSIHIFDTLLHmggvyWFCNNLIKELLKETR
  894-  940 (82.53/51.78)	RDPLNRVLANLF..LLISSILGSRTAGPHTQFVQ.....WFMEECVDCLEQGSR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     559.85|     197|     254|      87|     300|       3
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   44-  235 (233.94/200.22)	.........................EALLEQAMIGPS.....PNPLILSYLKYAISSQMVSySSVLT......................aiskfdDFSRD........LCVQALLDIMDMFCDrLSCHG.KAEECIGlcRALLS..ALHWLLRCTAAS...AERLREGLEAG.TPAAGekqlaMCLqRLEKTLSstknrallHIAKLEEASSWTAIEHCLLKLGEILANLSNHQLRSQAEQCGTL...IRSIPTM..LSVH.SEQ
  236-  481 (283.53/195.24)	LHKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQH.IPTPLFILEIWKACFVGLIE.SPEGTgelkwtaftflkipqvlvklkkyshgdkDFTEDvntafeflLKLTPLLDKADQRCN.CDCTNfLLQECSK..QGLLSeaSMNNLMAKRKADrehAPQLKSDENANiQPNPG.....LIL.RAEPTVT........NILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLksfARKFINLneFTTHrSEE
  492-  552 (42.37/16.78)	LFDISFLMLCHVAQTYGSEVILSESNTGGEVFFFETWMQTcMPEEGKILNPDHPCF......RPDST......................................................................................................................................................................................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.14|      51|     116|     650|     701|       4
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  650-  701 (86.26/57.93)	LYSENTLQFYNERVVIMSSILEHMCADVlQQTATQIKFPSTGMDTMPYWNLL
  768-  818 (89.88/56.29)	LYSVFCLDMQQATLVLLGHILPGLLTDS.SKWHSLMDPPGTALAKLAVWCAL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26916 with Med24 domain of Kingdom Metazoa
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